by Okinawa Institute of Science and Technology When encapsidated in budding HIV-1 virions, APOBEC3G (A3G) suppresses viral amplification by modifying the viral genome after reverse transcription in infected cells (left). But HIV-1 Vif catalyzes degradation of A3G, leading to infectious virions (right). Credit: OIST The HIV-1 virus can neutralize cellular defenses with its viral infectivity factor...
