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Intravenous ferric carboxymaltose linked to lower risk of heart failure hospitalizations in iron-deficient patients

Reviewed by Megan Craig, M.Sc. In iron-deficient patients with heart failure and reduced or mildly reduced left ventricular ejection fraction, intravenous ferric carboxymaltose (FCM) is associated with a reduced risk of the composite outcome of total cardiovascular hospitalization and cardiovascular death through 52 weeks compared with placebo, according to late-breaking research presented in a Hot...

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COVID hospitalizations climb 22% this week — and the CDC predicts further increases as new variants spread

BY ALEXANDER TIN The Centers for Disease Control and Prevention is now forecasting an acceleration in new COVID-19 hospitalizations over the coming month, the agency said this week, replacing a previous projection that admissions would “remain stable or have an uncertain trend.” It comes as health officials are racing to study a new highly mutated...

Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths
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Some antivirals used in nonsevere COVID-19 may reduce hospitalizations and deaths

by Canadian Medical Association Journal A colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAID The antiviral drugs molnupiravir and nirmatrelvir–ritonavir (Paxlovid), when used to treat nonsevere COVID-19, most likely reduce the risk of subsequent progression to hospitalization and death, according to new research published in CMAJ (Canadian Medical Association Journal). As most trials have focused...

COVID-19 study good news for rheumatic disease patients on immunosuppressants
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COVID-19 study good news for rheumatic disease patients on immunosuppressants

A European League Against Rheumatism (EULAR) database containing information on the effects of COVID-19 on patients with rheumatic and musculoskeletal diseases has given some reassurance to patients taking immunosuppressants. The drugs studied by the team include anti-malarial drugs, methotrexate, biological therapies such as TNF-alpha inhibitors, and nonsteroidal anti-inflammatory drugs such as Naproxen. None of them...

FDA approves Farxiga for heart failure with reduced ejection fraction
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FDA approves Farxiga for heart failure with reduced ejection fraction

The U.S. Food and Drug Administration has granted approval for Farxiga (dapagliflozin) oral tablets to treat adults with heart failure with reduced ejection fraction, the agency announced Tuesday. Farxiga is the first approved sodium-glucose cotransporter 2 inhibitor to treat adults with New York Heart Association functional class II to IV heart failure with reduced ejection...

Risks of potentially inappropriate medications post-hospitalization for older adults
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Risks of potentially inappropriate medications post-hospitalization for older adults

by American Geriatrics Society “Potentially inappropriate medications (PIMs)” are treatments that sometimes pose risks that outweigh their benefits, particularly for people who are 65 or older. About 20 to 60 percent of older adults take medicines that may be potentially inappropriate. That can increase the risk for being hospitalized, needing to visit the emergency department,...

Gastrointestinal symptoms common in COVID-19 patients, study reports
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Gastrointestinal symptoms common in COVID-19 patients, study reports

by Tracie White, Stanford University Medical Center Researchers found that, in addition to upper respiratory symptoms, a significant number of those sick with the new virus also suffered from loss of appetite, nausea, vomiting and diarrhea. The study, one of the earliest on U.S. patients with the coronavirus, was published online April 10 in Gastroenterology....

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When is best time to get flu shot? Analysis compares scenarios

UNIVERSITY OF PITTSBURGH PITTSBURGH, March 14, 2019 – When flu season peaks after mid-winter, tens of thousands of influenza cases and hundreds of deaths can likely be avoided if older adults wait until October to get their flu immunization, a University of Pittsburgh School of Medicine analysis reveals in the April issue of the American Journal of Preventive Medicine.  The protection offered by the flu vaccine...