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First-line immune defenses against COVID-19 are short-lived and may explain reinfection
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First-line immune defenses against COVID-19 are short-lived and may explain reinfection

by Imperial College London Credit: Unsplash/CC0 Public Domain A new study finds that antibodies produced in the nose decline nine months after COVID-19 infection, while antibodies found in the blood last at least a year. Antibodies in the nasal fluid (known as immunoglobulin A, or IgA) provide first-line defense against COVID-19 by blocking SARS-CoV-2 virus...

How immune defenses are able to curb coronavirus and prevent pneumonia
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How immune defenses are able to curb coronavirus and prevent pneumonia

by Ludwig Maximilian University of Munich Graphical abstract. Upper left: schematic of the combined patient cohorts used. Upper right: Schematic of experimental setup. The study was divided into an exploratory cohort using scRNA-Seq, multidimensional flow cytometry of PBMCs, and shotgun plasma proteomics. The confirmation cohort was used to validate findings from the exploratory cohort, using...