Columbus, Ohio – A new study led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Solove Research Institute (OSUCCC – James) has identified a protein within certain immune cells that is required for optimal immune responses to cancer. The findings, reported in the journal Science Advances,...
Tag: <span>Immune system</span>
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Coronavirus: Dexamethasone proves first life-saving drug
By Michelle Roberts Health editor, BBC News online A cheap and widely available drug can help save the lives of patients seriously ill with coronavirus. The low-dose steroid treatment dexamethasone is a major breakthrough in the fight against the deadly virus, UK experts say. The drug is part of the world’s biggest trial testing existing...
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Two new, powerful small molecules may be able to kill cancers that other therapies can’t
Using human cell and mouse models, City of Hope scientists demonstrate that the cancer inhibitors they’re developing could destroy acute myeloid leukemia and tumors from brain, pancreatic and breast cancers PRINT E-MAIL DUARTE, Calif. — City of Hope scientists have identified and developed two potent small molecules that appear to suppress tumor growth in multiple...
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Improved gut microbiota with cholesterol-lowering medication
by Margareta Gustafsson Kubista, University of Gothenburg There is a clear link between improved gut microbiota and one of our most common cholesterol-lowering drug groups: statins. This is evident from a European study involving researchers from the University of Gothenburg. Scientists have previously found an association between the gut microbiota and various metabolism-related and cardiovascular...
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Diabetic mice improve with retrievable millimeter-thick cell-laden hydrogel fiber
INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO CREDIT: INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO Tokyo, Japan – Type 1 diabetes mellitus (T1DM) results from an irreversible autoimmune destruction of insulin-producing pancreatic β-cells requiring life-long substitution of insulin. In a new study, researchers at the Institute of Industrial Science, The University of Tokyo...
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Muscles support a strong immune system
GERMAN CANCER RESEARCH CENTER (DEUTSCHES KREBSFORSCHUNGSZENTRUM, DKFZ) PRINT E-MAIL In the fight against cancer or chronic infections, the immune system must be active over long periods of time. However, in the long run, the immune defence system often becomes exhausted. Scientists at the German Cancer Research Center (DKFZ) have now found initial evidence in mice...
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COVID-19 immune response may remain stable for two months after diagnosis
by St. George’s University of London Initial results from an antibody testing study have revealed that COVID-19 antibodies remain stable in the blood of the majority of infected individuals almost two months after diagnosis and possibly longer. However, antibodies were not detectable in everyone exposed to the virus, opening discussions on how best to interpret...
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T cells engineered to target senescence
Senescence is a hallmark of cellular ageing and contributes to many diseases. A new method enabling immune cells to target senescent cells might offer improved therapeutic options. Senescence is a form of cellular stress response. In some circumstances it can be harmful, and efforts are under way to develop therapies that target senescent cells. Writing...
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Nanosponges could intercept coronavirus infection
UNIVERSITY OF CALIFORNIA – SAN DIEGO Nanoparticles cloaked in human lung cell membranes and human immune cell membranes can attract and neutralize the SARS-CoV-2 virus in cell culture, causing the virus to lose its ability to hijack host cells and reproduce. The first data describing this new direction for fighting COVID-19 were published on June...
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New drug candidate reawakens sleeping HIV in hopes of functional cure
by Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV). The research, published in Cell Reports Medicine, aims to create a functional HIV cure by activating and then eliminating all pockets of...