by University of Nottingham Credit: Unsplash/CC0 Public Domain A major clinical trial, led by experts at the University of Nottingham, has shown that people with inflammatory conditions are able to improve the antibody response from a COVID-19 booster vaccination by interrupting their treatment for two weeks immediately after having the vaccine. The antibody response to the...
Tag: <span>Immunity</span>
Covid-19 has changed and so has our immunity. Here’s how to think about risk from the virus now
By Brenda Goodman, CNNUpdated 7:58 AM EDT, Mon August 28, 2023 Experts say it’s less risky to catch Covid-19 than it used to be, but there are still good reasons not to treat it casually.Daly and Newton/The Image Bank RF/Getty ImagesCNN—Covid-19 was never just another cold. We knew it was going to stick around and...
The interplay between immunity, the nervous system, and microbiota
By Dr. Priyom Bose, Ph.D. Aug 15 2023 Reviewed by Benedette Cuffari, M.Sc. A recent Immunity review analyzes the influence of the gut microbiota on neural and immune networks. Understanding the association between these seemingly isolated entities could contribute to the development of novel therapies and interventions. Study: Boundaries and integration between microbiota, the nervous system, and immunity....
How immunity contributes to ageing and neurodegeneration
ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE IMAGE: AN ACTIVATED MICROGLIAL CELL IN THE BRAIN OF CGAS/STING ACTIVATED MICE. CREDIT: GULEN ET AL. NATURE 02 AUGUST 2023. DOI: 10.1038/S41586-023-06373-1 As we age, our bodies undergo various changes that can impact our overall health and make us more susceptible to diseases. One common factor in the ageing process...
How your first brush with COVID warps your immunity
Rachel Brazil Illustration by Kasia Bojanowska During the summer of 2022, with the Omicron coronavirus variant running rampant, friends and relatives of immunologist Bob Seder kept asking him if they should postpone their COVID-19 boosters and wait for the new Omicron-tailored vaccine to become available. He told them not to delay. Seder, acting chief of...
Breast cancer vaccine safely generates anti-tumor immunity
by Michael McCarthy., University of Washington Three-dimensional culture of human breast cancer cells, with DNA stained blue and a protein in the cell surface membrane stained green. Credit: NCI Center for Cancer Research, National Cancer Institute, National Institutes of Health An experimental vaccine against breast cancer safely generated a strong immune response to a key...
Newly discovered barrier prevents immunity from reaching smell-sensing cells
DUKE UNIVERSITY IMAGE: CIRCULATING ANTIBODY (WHITE) IS PREVENTED FROM ACCESSING OLFACTORY EPITHELIUM BY A PREVIOUSLY UNKNOWN BLOOD-OLFACTORY BARRIER, THE BOB. THIS NEWLY IDENTIFIED BARRIER KEEPS SOME OF THE LARGER MOLECULES OF THE BODY’S IMMUNE SYSTEM OUT OF OLFACTORY EPITHELIUM (GREEN), LEAVING A GAP IN PROTECTION MAY EXPLAIN TWO MYSTERIES OF COVID. CREDIT: ASHLEY MOSEMAN LAB,...
Scientists discover antibodies that induce broad immunity against SARS viruses, including emerging variants
by The Scripps Research Institute Macaque antibodies were shown to induce a much broader immune response against SARS-related viruses, including emerging variants, which could help with the development of new human vaccines. Human CC12.1 (purple) and macaque K398.22 (orange) antibodies bind to different regions of the receptor binding domain (RBD) on SARS-CoV-2 (white). Credit: Scripps Research...
Bacterial bullseye: In rare feat, researchers decipher how one gut bacterium influences immunity
by Harvard Medical School Credit: CC0 Public Domain From immunity to metabolism to mental health, it seems like the gut microbiome has been linked to every aspect of human health and disease. But with hundreds of bacterial species populating our gastrointestinal tract, it’s a daunting task to pinpoint which molecules made by which bacteria affect which biological processes—and...
Researchers develop antibody test to keep track of immunity to SARS-CoV-2 variants
by University of Toronto Professor Igor Stagljar and Dr. Zhong Yao co-developed the first-in-class method for measuring Sars-CoV-2 neutralizing antibodies. Credit: Stagljar lab, University of Toronto The experts agree—the pandemic is not over. Infections are ticking up again, fueled by the new variants our immune systems are ill prepared for. That’s according to a study by...