August 1, 2024 by Eindhoven University of Technology Schematic overview of the study. Credit: Nature Nanotechnology (2024). DOI: 10.1038/s41565-024-01727-wWithin an international collaboration of 30 scientists, TU/e professors Jan van Hest and Willem Mulder are working on nanotechnological research to accurately stimulate the immune system. The TU/e team is focusing on the behavior of polymersomes that...
JULY 12, 2024 by Stefan Zorn, Medizinische Hochschule Hannover Jurkat cells adhere better to cells infected with the VZV-gC-GFP virus than with VZV-ΔgC-GFP. a) Schematic representation of the assay. b–d) Each circle corresponds to one independent experiment. e) Representative fluorescence microscopy images of Jurkat and HaCaT cells in the four experimental conditions. Credit: Nature Communications...
by Liz Ahlberg Touchstone, University of Illinois at Urbana-Champaign The team uses an inverted fluorescence microscope to image cancer cells that are targeted using different light spectra to initiate inflammatory cell death. The process could help create immunotherapy techniques for disease intervention. Credit: Fred Zwicky, University of Illinois at Urbana-ChampaignA new method of precisely targeting...
A trial HIV vaccine has triggered broadly neutralizing antibodies in humans after just two immunizations.News Published: May 20, 2024 | Blake Forman Read time: 3 minutes Infection with HIV is currently manageable with lifelong antiretroviral medications, but neither a vaccine nor a cure is available. A critical roadblock in preventative vaccine development has been the...
by University of Cambridge Credit: Pixabay/CC0 Public Domain An increase in nightmares and hallucinations—or ‘daymares’—could herald the onset of autoimmune diseases such as lupus, say an international team led by researchers at the University of Cambridge and King’s College London. The researchers argue that there must be greater recognition that these types of mental health...
by Karolinska Institutet Credit: CC0 Public Domain A new study from Karolinska Institutet in Sweden reveals that immune cells in the liver react to high cholesterol levels and eat up excess cholesterol that can otherwise cause damage to arteries. The findings, published in Nature Cardiovascular Research, suggest that the response to the onset of atherosclerosis...
by University of Saskatchewan Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.110856 The body’s innate immune system, active from birth, is the first line of defense against viruses and other pathogens that cause disease. Using vaccination as an example, after receiving a vaccine, pain, redness, or swelling may occur at the injection site. This response is a...
by University of Tokyo Credit: Pixabay/CC0 Public Domain Why did Japan largely contain COVID-19 despite famously jam-packed Tokyo and despite the country’s proximity to China? With no penalties and only requests for cooperation, Japan’s state of emergency somehow averted the large-scale outbreaks seen elsewhere. At least one viable answer has now emerged. A new comparative analysis...
Proenkephalin+ regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function NAGOYA CITY UNIVERSITY UVB IRRADIATION INDUCES PROLIFERATION AND ACTIVATION OF SKIN TREG CELLS. UVB-EXPANDED SKIN TREG (UVB-SKIN TREG) CELLS PROMOTE WOUND HEALING BY PRODUCING ENKEPHALIN AND AMPHIREGULIN(AREG), WHICH ENHANCE KERATINOCYTE GROWTH/PROLIFERATION TO REPAIR… view more CREDIT: DEPARTMENT IMMUNOLOGY, NAGOYA...
by Jacqueline Carey, University of Illinois at Chicago Macrophages are white blood cells that, depending on the signals they get from the immune system, become specialized in either increasing or decreasing inflammation. When macrophages are programmed to be pro-inflammatory, they help to increase inflammation, which is beneficial for fighting infections; when they are programmed to...
