Donavyn Coffey Artificial intelligence can distinguish overlapping inflammatory conditions with total accuracy, according to a new study presented (abstract 2040) on November 14 at the 2023 annual meeting of the American College of Rheumatology. Texas pediatricians faced a conundrum during the pandemic. Endemic typhus, a flea-borne tropical infection common to the region, is nearly indistinguishable...
Tag: <span>inflammatory disease</span>
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Future therapies for managing inflammatory bowel disease
Peer-Reviewed Publication FIRST HOSPITAL OF JILIN UNIVERSITY ANTITUMOUR NECROSIS FACTOR ALPHA (ANTI-TNFΑ) AGENTS INCLUDE INFLIXIMAB, ADALIMUMAB, GOLIMUMAB, AVX-470 AND OPRX-106. JANUS KINASE (JAK) INHIBITORS: TOFACITINIB, FILGOTINIB AND UPADACITINIB. CYTOKINE INHIBITORS: USTEKINUMAB, WHICH TARGETS INTERLEUKIN (IL) 12, SUBUNIT P40/P35; RISANKIZUMAB, MIRIKIZUMAB, GUSELKUMAB AND BRAZIKUMAB TARGET IL-23, SUBUNIT P40/P19. SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR MODULATORS: AMISELIMOD, OZANIMOD, ETRASIMOD AND...
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FDA approves Wezlana for multiple inflammatory diseases
by Lori Solomon The U.S. Food and Drug Administration has approved Amgen’s Wezlana (ustekinumab-auub) as a biosimilar to and interchangeable with Stelara (ustekinumab) for multiple inflammatory diseases. The approval includes indications for adults with moderate-to-severe plaque psoriasis who are candidates for phototherapy or systemic therapy, active psoriatic arthritis, moderately to severely active Crohn disease, and...
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Cancer drug could hold hope for treating inflammatory diseases including gout and heart diseases
by University of Cambridge Graphical abstract. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI162129 A cancer drug currently in the final stages of clinical trials could offer hope for the treatment of a wide range of inflammatory diseases, including gout, heart failure, cardiomyopathy, and atrial fibrillation, say scientists at the University of Cambridge. In a study,...
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Neuroimmune Modulation for Inflammatory Disease: Interview with Dr. Simhambhatla, President and CEO of SetPoint Medical
FEBRUARY 28TH, 2023 CONN HASTINGS EXCLUSIVE, MEDICINE, NEUROLOGY SetPoint Medical, a medtech company based in California, is developing a neuromodulatory device that is intended to treat rheumatoid arthritis. The overlap between the nervous and immune systems is increasingly appreciated, and this technology aims to capitalize on this to create a new treatment for inflammatory disease. The...
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Mouse model shows obesity in early life promotes later inflammatory disease, even after weight loss
by Bob Yirka, Medical Xpress Credit: CC0 Public Domain A team of researchers affiliated with multiple institutions in Canada has found that obesity in young mice can lead to inflammatory disease later in life even if the mouse is no longer overweight. In their paper published in the journal Science, the group describes studying early life obesity in...
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Carbon Monoxide-Loaded Foam as Inflammatory Disease Treatment
JULY 7TH, 2022 CONN HASTINGS GI, MATERIALS, MEDICINE Researchers at MIT have created a carbon monoxide-loaded foam intended for therapeutic use against inflammatory disease. While the gas is toxic if inhaled in large quantities, in small doses it has potent anti-inflammatory effects. However, delivering it to the gastrointestinal tract to treat inflammatory diseases, such as colitis,...
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New approach to treating arthritis and other inflammatory diseases
by Peter MacCallum Cancer Centre Researchers from Peter Mac have discovered an innovative way to dampen severe inflammation in mice, uncovering a potential new therapeutic approach for inflammatory and autoimmune conditions such as arthritis, psoriasis and liver disease, as well as some cancers. The research, co-led by Prof Mark Dawson’s laboratory, in collaboration with scientists...
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Oral steroids put patients with inflammatory disease at high risk of infection
JOULE INC. Oral steroid use in patients with the inflammatory diseases polymyalgia rheumatica and/or giant cell arteritis significantly increased the risk of infection, and the risk increased with higher doses, found a study in CMAJ (Canadian Medical Association Journal). In a large study of almost 40 000 adult patients with polymyalgia rheumatica or giant cell arteritis in England, researchers found higher absolute risks of infectionwhen patients were taking oral steroids than when they were not...
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Cannabidiol is a powerful new antibiotic
by American Society for Microbiology New research has found that Cannnabidiol is active against Gram-positive bacteria, including those responsible for many serious infections (such as Staphyloccocus aureus and Streptococcus pneumoniae), with potency similar to that of established antibiotics such as vancomycin or daptomycin. The research is presented at ASM Microbe, the annual meeting of the American Society for Microbiology....
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