by University of Bonn If the mitochondria (light blue) are damaged, the NLRP10 “smoke detector” sounds the alarm and forms with other proteins into an inflammasome (red). Ultimately, this leads to the demise of the cell and its disposal. Credit: Kim S. Robinson/Skin Research Institute Singapore Researchers at the Universities of Bonn and Singapore have discovered a new...
Report: How a protein protects cells from death UNIVERSITY OF HOUSTON RAJ KUMAR, CLINICAL PROFESSOR OF BIOCHEMISTRY, UNIVERSITY OF HOUSTON COLLEGE OF MEDICINE, FOUND A MECHANISM FOR HOW THE PROTEIN, CALLED NUCLEAR FACTOR OF ACTIVATED T CELLS 5 (NFAT 5), WORKS… view more CREDIT: UNIVERSITY OF HOUSTON A University of Houston College of Medicine researcher...
by Ludwig Maximilian University of Munich The immune system: Knocked off balanceInstead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. An LMU team has dissected how mast cells regulate their calcium levels to keep the immune response under control. Credit: IMCES UK Essen/LMU Instead...
by Harvard Medical School The aberrant buildup of misfolded proteins is a hallmark of a host of disorders, including neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Aggregates of these toxic proteins wreak havoc on the function of cells, tissues, and organs, and despite intensive research over many decades, there are still no effective means to...
By Sara Ryding, B.Sc. Reviewed by Emily Henderson, B.Sc. Viral load refers to the amount of virus in an infected person’s blood. This is expressed as the number of viral particles in each milliliter of blood. Higher viral load can have different implications for different viruses but typically means the infection is progressing. Viral load...
Sponsored Content by BMG LABTECH GmbH Currently in developed countries, life expectancy is far higher than 80 years of age. However, with a longer life expectancy comes increased chances of developing a neurodegenerative disease, like Alzheimer’s disease, Parkinson’s disease and dementia. The progression of these disorders result in an increasingly debilitating situation until full-time care...
Research team of Alexey Amunts in collaboration with AstraZeneca unravel the extracellular region of the receptor tyrosine kinase RET involved in degenerative diseases. SCIENCE FOR LIFE LABORATORY The study published in Science Advancesreveals the mechanism by which the receptor tyrosine kinase RET can increase neuronal survival in degenerative diseases. To understand the mechanism of this signalling...
