Tag: <span>Kidney disease</span>

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Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease
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Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease

KAROLINSKA INSTITUTET IMAGE: PRINCIPAL INVESTIGATOR JUAN JESUS CARRERO, PROFESSOR AT THE DEPARTMENT OF MEDICAL EPIDEMIOLOGY AND BIOSTATISTICS AT KAROLINSKA INSTITUTET IN SWEDEN. v CREDIT: ULF SIRBORN. Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such...

Mild electrical stimulation with heat shock ameliorates kidney disease
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Mild electrical stimulation with heat shock ameliorates kidney disease

KUMAMOTO UNIVERSITY IMAGE: MES+HS AMELIORATES THE RENAL PATHOLOGY OF ADR-INDUCED NEPHROTIC SYNDROME BY REGULATING THE AKT-BAD PATHWAY, EXERTING ANTI-APOPTOTIC EFFECTS, AND INHIBITING INFLAMMATION AND FIBROSIS. CREDIT: PROFESSOR HIROFUMI KAI A research team from Kumamoto University in Japan has found that the combination of weak pulsed electrical current and heat exerts anti-inflammatory and anti-fibrotic effects in...

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DOCTORS USE GRAPHENE TO INVENT CHEAP, EASY TEST FOR KIDNEY DISEASE

BY DAN ROBITZSKI Using graphene, a nanomaterial made of carbon that’s just one atom thick, scientists say they’ve made a cheap, more accessible antibody test for kidney disease. The goal, the University of Manchester researchers say in a press release, was to make a test that measures specific antibodies quickly at the doctor’s office, rather than in whatever...

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Newer Type 2 diabetes medications have heart and kidney disease benefits, too

AMERICAN HEART ASSOCIATION DALLAS, Sept. 28, 2020 — Two newer groups of medications prescribed primarily for Type 2 diabetes treatment (SGLT2 inhibitors and GLP-1 receptor agonists) could significantly reduce risks associated with chronic kidney disease (CKD) and heart disease. Based on analyses of the clinical trials through March 2020, a group of leading experts in diabetes, heart...

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SGLT2 inhibitors can slow progression of chronic kidney disease

Two randomized controlled studies [1, 2] show: SGLT2 inhibitors can slow CKD progression in all patients, not only in patients with diabetes 850 million people worldwide are affected by chronic kidney disease (CKD) – a worrying figure, and one that continues to rise. Treatment options for patients with CKD are multiple and often determined by...

Protein discovery could improve type 2 diabetes treatment
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Protein discovery could improve type 2 diabetes treatment

by University of Melbourne A world first discovery of how a protein works in the liver could lead to a more effective type 2 diabetes drug. The University of Melbourne-led study found that the SMOC1 protein, which is naturally produced by the liver, can decrease blood glucose levels. An engineered form of SMOC1 could therefore...

World-first study on blood hormone could reduce cardiovascular deaths
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World-first study on blood hormone could reduce cardiovascular deaths

by Kim Thomas, University of Otago A simple blood test could identify seemingly-healthy people with a high hidden risk of heart disease thanks to a world-first discovery by University of Otago, Christchurch researchers. Researchers from the University’s Christchurch Heart Institute studied the blood samples and cardiology scans of 665 healthy young and middle-aged people with...

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Does high blood sugar worsen COVID-19 outcomes?

Preliminary observations of COVID-19 patients with diabetes inspired an algorithm for glucose monitoring that’s suspected to help combat the virus’ serious complications MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN As COVID-19 continues to rage across the U.S., researchers are digging deeper into how the virus wreaks havoc on the body, especially for those with a pre-existing...

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The yin and yang of inflammation controlled by a single molecule

Researchers from the Perelman School of Medicine at the University of Pennsylvania have now identified a protein called histone deacetylase 3 (HDAC3) as the orchestrator of the immune system’s inflammation response to infection. By using both specially cultured cells and small animal models, HDAC3 was found to be directly involved in the production of agents...