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Turning immune cells into killers
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Turning immune cells into killers

by  University of Würzburg Liver tissue with innate lymphoid cells (ILCs), visualised here as red dots. Credit: Ye Ouyang / University of Wuerzburg When pathogens invade the human body, a rapid response is required. At the forefront of the immune response are special immune cells. They reside in various tissues such as the lungs, liver, skin...

The first systematic way to catch natural killer cells and get them to release cancer-killing packets called exosomes
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The first systematic way to catch natural killer cells and get them to release cancer-killing packets called exosomes

MICHIGAN MEDICINE – UNIVERSITY OF MICHIGAN IMAGE: TWO LARGE NATURAL KILLER IMMUNE CELLS ARE SURROUNDED BY THEIR MUCH SMALLER EXOSOMES ON THE NK-GO MICROFLUIDIC CHIP DEVELOPED AT THE UNIVERSITY OF MICHIGAN. CREDIT: IMAGE COURTESY OF YOON-TAE KANG AND ZEQI NIU. Building on the promise of emerging therapies to deploy the body’s “natural killer” immune cells...

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Engineered killer immune cells target tumours and their immunosuppressive allies

Natural killer immune cells engineered to target the PD-L1 molecule can directly kill tumour cells in mice and reduce the numbers of immunosuppressive cells harbouring PD-L1 in mice and humans Scientists have engineered natural killer immune cells that not only kill head and neck tumour cells in mice but also reduce the immune-suppressing myeloid cells...

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Killer cell immunotherapy offers potential cure for advanced pancreatic cancer

A new approach to treating pancreatic cancer using ‘educated killer cells’ has shown promise, according to early research by Queen Mary University of London QUEEN MARY UNIVERSITY OF LONDON The new cell-based immunotherapy, which has not yet been tested in humans with pancreatic cancer, led to mice being completely cancer-free, including cancer cells that had already spread to the liver...