Tag: <span>‘Leaky’ activity</span>

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‘Leaky’ activity of mutated enzyme underlies neurodegenerative disease
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‘Leaky’ activity of mutated enzyme underlies neurodegenerative disease

by University of California – San Diego Patients with spinocerebellar ataxia type 14 display cerebellar atrophy (right, green arrow) compared to age-matched healthy controls (left). Credit: UC San Diego Health Sciences Spinocerebellar ataxias are a group of neurodegenerative diseases characterized by the degeneration of Purkinje cells, a major class of neurons in the cerebellum. The...