by Goethe University Frankfurt am Main Graphical abstract. Credit: iScience (2023). DOI: 10.1016/j.isci.2023.107844Leukemia is the most common type of cancer in children. Treatment involves intensive chemotherapy, which has severe side effects due to its non-specific mode of action. A team from the Department of Pediatrics and the Institute for Experimental Pediatric Hematology and Oncology at...
by Peggy Darius, Leipzig University Graphical abstract. Credit: Cancer Research (2022). DOI: 10.1158/0008-5472.can-21-1908 Although there has been significant progress in the treatment of rare forms of blood cancer in recent years and new drugs have been approved in Germany, the prognosis for many affected individuals remains unfavorable. Research teams at Leipzig University’s Faculty of Medicine are working...
by Queen Mary, University of London Credit: Unsplash/CC0 Public Domain Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells. By rewiring the inner workings of the cancer cells, the team was able prime...
by University of Geneva Graphical abstract. Credit: DOI: 10.1016/j.celrep.2021.110197 Acute myeloid leukemia, which affects blood and bone marrow cells, is a particularly dangerous form of cancer. More than half of patients under the age of 60 die. This proportion rises to 85% for patients over 60. A team from the University of Geneva (UNIGE), Switzerland,...
by Newcastle University Fig. 1: Manhattan plot from chronic lymphocytic leukemia meta-analysis of 6 genome-wide association studies for variants associating with progressive disease. Credit: Nature Communications (2021). DOI: 10.1038/s41467-020-20822-9 Scientists have identified a way of predicting early whether patients will develop a common type of leukemia, based on their genetics. Newcastle University co-led the study, published in Nature...
