by American Association for the Study of Liver Diseases Credit: Pixabay/CC0 Public Domain Liver disease, which is treatable when discovered early, often goes undetected until late stages, but a new study revealed that an algorithm fueled by artificial intelligence can accurately detect early-stage metabolic-associated steatotic liver disease (MASLD) by using electronic health records. The study...
Tag: <span>liver disease</span>
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Gut hormones could hold the key to fighting fatty liver disease
The accumulation of fats in the liver is driven by high-fat diets and obesity, and is becoming an increasingly prevalent global health concern. Characterized by excessive fat accumulation in the liver, this condition poses significant risks for various metabolic disorders. While much of the existing research has focused on fat metabolism within the liver itself,...
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A novel liver patch could help treat and prevent liver disease
JUNE 12, 2024 by Wiley Credit: Unsplash/CC0 Public DomainAs described in research published in the Biotechnology Journal, investigators have developed a novel patch that can help liver tissue regenerate. The patch is a combination of decellularized liver matrix, a liver growth factor, and an anticoagulant. In lab tests with liver cells, the patch helped liver...
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What are the links between liver disease and the microbiome?
Content by Owlstone Medical LtdReviewed by Louis Castel The gut-liver axis is the term used to describe the two-way relationship between the gut microbiome and the liver. This relationship stems from the integration of signals produced by various factors such as diet, genetics, and the environment. The liver and the gastrointestinal tract are connected by...
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FDA approves Madrigal’s NASH drug, marking the first-ever treatment for the liver disease
FDA approves Madrigal’s NASH drug, marking the first-ever treatment for the liver diseaseNicole DeFeudisEditorMadrigal Pharmaceuticals’ NASH drug won an accelerated approval on Thursday, becoming the first treatment for a liver disease that for years has vexed scientists and investors. The medication, resmetirom, was approved under the brand name Rezdiffra for patients with stage 2 and...
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New Insights: Liver Disease and Dementia Connection
ByEthan SullivaA recent study suggests an intriguing connection between dementia and liver disease. The research implies that some cases of dementia may be linked to liver health, suggesting that this connection could be treatable and potentially reversible. This new understanding could be a game-changer in the management and treatment of dementia cases linked to liver...
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Study: Women with alcohol-related liver disease have greater mortality risk than men with condition
by Cedars-Sinai Medical Center Credit: Pixabay/CC0 Public DomainInvestigators from the Smidt Heart Institute at Cedars-Sinai and colleagues found that women with fatty liver disease related to alcohol consumption have almost twice the risk of dying within a certain time period than men with the same condition. The findings, published in the Journal of Hepatology, highlight the...
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Hepatic TRPC3: An emerging regulator of alcohol-associated liver disease
by Higher Education Press The proposed model of hepatic TRPC3-regulated ALD. Credit: Qinchao Ding, Rui Guo, Liuyi Hao, Qing Song, Ai Fu, Shanglei Lai, Tiantian Xu, Hui Zhuge, Kaixin Chang, Yanli Chen, Haibin Wei, Daxi Ren, Zhaoli Sun, Zhenyuan Song, Xiaobing Dou, Songtao LiExcessive alcohol intake is strongly associated with alcohol-associated liver disease (ALD) which...
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Gut microbes revealed as key players in liver disease solutions
Chinese Academy of SciencesIn the editorial published on 4 September 2023, in the “gut-liver axis” special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota...
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Novel stem cell therapy using mRNA technology may stimulate natural repair in liver disease
by Boston Medical Center Graphical Abstract. Credit: Cell Stem Cell (2023). DOI: 10.1017/j.stem.2023.10.008 Mortality related to end stage liver disease is ranked as the 12th most common cause of death in the U.S. Liver transplantation remains the only treatment for end stage liver disease, but there is a critical shortage of organ donors, necessitating a dire...