August 13, 2024 by Matt Shipman, North Carolina State University Examples of histology slides corresponding to modified Ashcroft scores 0–4, for H&E (top) and Masson’s trichrome (bottom) staining. Viewed at 100 × total magnification. Scale bar = 200 microns. Credit: Scientific Reports (2024). DOI: 10.1038/s41598-024-66390-6Researchers have established a suite of parameters that can be determined using ultrasound to quantitatively...
Tag: <span>Lung disease</span>
How shortened telomeres heighten risk of serious lung disease
by Mayo Clinic Human chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASA In 2017, Cindy Sutherland caught a nasty cold she couldn’t shake. After coughing nonstop for weeks, she went to urgent care and got a chest X-ray. When the doctor shared the results with her, he asked, “Have you ever heard of pulmonary fibrosis?”...
Discovered the epigenetic scars that the COVID-19 disease causes in the lung
Peer-Reviewed Publication JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE MANEL ESTELLER, VERONICA DAVALOS, ALEIX NOGUERA-CASTELLS AND EVA MUSULEN, JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE. AUTHORS OF THE STUDY ABOUT THE EFFECT OF LETHAL COVID-19 IN THE EPIGENETICS OF THE LUNG TISSUES CREDIT: JOSEP CARRERAS LEUKAEMIA RESEARCH INSTITUTE. The COVID-19 disease, due to infection with the SARS-CoV2 virus, became...
Study suggests millions of long-term smokers have lung disease that defies diagnosis
by University of California, San Francisco Credit: Pixabay/CC0 Public Domain Millions of Americans with tobacco-related lung disease have symptoms that do not fit any existing tobacco-related disease criteria—including the most common of those, chronic obstructive pulmonary disease (COPD)—according to a new study led by researchers at UC San Francisco. In a study published Aug. 1, 2023,...
Researchers find potential therapy for rare but devastating lung disease
by Bill Bangert, University of Cincinnati Tasnim Olatoke, graduate student in the UC College of Medicine. Credit: Andrew Higley/UC Marketing + Brand A treatment for a rare cancer-like lung disease found in women of childbearing age may have been discovered by University of Cincinnati researchers. The rare lung disease is called lymphangioleiomyomatosis or LAM, and the cause of it...
AI diagnoses lung disease based on X-rays
by Skolkovo Institute of Science and Technology The first row contains lung X-ray images. The second row lists the diagnoses made by human radiologists. These are elaborated in the paragraphs provided in the third row. The bottom row contains comparable captions generated by the neural networks. The underlined fragments show that, while the text could clearly...
Prompt recognition and treatment found effective for lung disease in patients who received new drug for advanced cancer
THE MOUNT SINAI HOSPITAL / MOUNT SINAI SCHOOL OF MEDICINE Lung disease caused by a new drug for cancers—including metastatic or advanced breast cancer—can be effectively treated using approaches that focus on early detection and prompt management, according to a study published in ESMO Open on August 11, 2022. Using data from nine clinical trials, this study...
New biomarker speeds identification of lung disease
LAWSON HEALTH RESEARCH INSTITUTE LONDON, ON- A new diagnostic method could help identify one of the deadliest types of interstitial lung disease (ILD) sooner, allowing for faster treatment and improved patient outcomes. Idiopathic pulmonary fibrosis (IPF) is one of the most serious and common types of ILD, occurring most often in patients 60 and older...
New drug target identified for inflammatory lung disease
by Centenary Institute Credit: Pixabay/CC0 Public Domain Researchers at the Centenary Institute and the University of Technology Sydney have identified a new drug target for the treatment and prevention of chronic obstructive pulmonary disease (COPD), an inflammatory lung disease that causes airway blockage and that makes it difficult to breathe. Secreted by mast cells, a part...
Cell therapy for lung disease? Proof-of-concept study shows promise
by Nancy Fliesler, Children’s Hospital Boston Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.110662 Many serious pulmonary diseases, including genetic lung diseases, lack an effective treatment other than the most extreme: lung transplant. A team at Boston Children’s Hospital envisions a much better option: cell therapy, using lung stem cells created from patients’ own cells to repair...