MEDBRIEF Edited by Manasi Talwadekar August 12, 2024 TOPLINE:The first year after the diagnosis of systemic lupus erythematosus (SLE) is crucial, with the highest percentage of patients experiencing organ damage. Cardiovascular issues are the second most prevalent after musculoskeletal damage in both early and later stages of SLE. METHODOLOGY:Researchers assessed organ damage persisting at least...
Tag: <span>Lupus</span>
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Horrifying video shows in detail what mysterious disease that hit Lady Gaga and Selena Gomez does to the body
By Rebecca Whittaker For Mailonline Published: 06:36 EDT, 12 August 2024 | Updated: 08:11 EDT, 12 August 2024 A horrifying video of a woman whose heart and lungs stopped working shows the stark reality of lupus, the incurable disease that hit Selena Gomez and Lady Gaga. Melisa Woolery, 31, was diagnosed with the incurable condition...
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Studies discover single-gene mutation that can cause lupus
By Paul McClure Researchers have pinpointed a genetic mutation that can lead to lupusDepositphotos In two separate studies, German researchers have identified the single-gene mutation that can lead to the incurable autoimmune disease lupus. The discovery opens the door to developing new therapeutic approaches and testing for the mutation, which would ensure early diagnosis of the...
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New immune system-targeting compound shows early promise in treating lupus
by The Scripps Research Institute Chemoproteomic discovery of SLC15A4 inhibitors. Credit: Nature Chemical Biology (2024). DOI: 10.1038/s41589-023-01527-8Scientists from Scripps Research have developed a small molecule that blocks the activity of a protein linked to autoimmune diseases, including systemic lupus erythematosus (SLE) and Crohn’s disease. This protein, known as SLC15A4, has been considered largely “undruggable,” as most...
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Autoimmune patients in CAR-T study see striking improvements across lupus and other diseases
Autoimmune patients in CAR-T study see striking improvements across lupus and other diseasesLei Lei WuNews ReporterSAN DIEGO — All of the first 15 autoimmune disease patients who received CAR-T therapy at a German hospital saw the debilitating symptoms of their diseases, including lupus and myositis, substantially improve or go away entirely, according to new research...
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CAR-T cell therapy leads to long-term remission in lupus while maintaining vaccine response
by American College of Rheumatology Credit: CC0 Public Domain New research at ACR Convergence 2023, the American College of Rheumatology’s annual meeting, demonstrates that CAR-T cell therapy could lead to sustained suppression of autoantibodies in treatment-resistant lupus while maintaining a robust response to vaccines. Systemic lupus erythematosus (SLE, lupus) is a complex autoimmune disease marked by...
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Lupus and Beyond: Exploring the Common Comorbidities of this Autoimmune Disease
By Sarah Moore Reviewed by Danielle Ellis, B.Sc. Comorbidities are common in people with lupus. The autoimmune disease increases the risk of complications such as cardiovascular disease, cancer, and even mental health illnesses. Here, we explore some of the most common comorbidities in lupus. Image Credit: SewCreamStudio/Shutterstock.com Lupus and cardiovascular disease Cardiovascular disease has emerged...
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What to know about PCOS and lupus
Polycystic ovary syndrome (PCOS) is a hormonal condition that primarily affects the ovaries. Lupus is a chronic autoimmune disease that involves inflammation in multiple organs and body tissues. People with PCOS may be at increased risk of developing lupus and other autoimmune diseases. This article explores the potential link between PCOS and lupus and provides...
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What to know about chocolate and lupus
Chocolate and cocoa products may help reduce inflammation, which may benefit people with autoimmune conditions such as lupus. However, there is no conclusive evidence that chocolate can reduce lupus symptoms. Lupus is a chronic autoimmune disease that can affect different parts of the body. With an autoimmune disease, the immune system cannot tell the difference between healthy tissues and pathogens. It...
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How might lupus affect fingernails?
Lupus can cause a variety of symptoms. Some individuals may experience changes in their fingernails and toenails. This may involve discoloration, infections, and changes in nail shape. Lupus refers to a long-term autoimmune condition. It occurs when the immune system mistakenly attacks healthy tissue, which can result in several possible symptoms. Potential symptoms of lupus can include changes to skin and nails....