Batya Swift Yasgur, MA, LSW April 25, 2023 Major depressive disorder (MDD) is linked to disruptions in energy and lipid metabolism, possibly caused by the interplay of the gut microbiome and blood metabolome, new research suggests. Investigators found that MDD had specific metabolic “signatures” consisting of 124 metabolites that spanned energy and lipid pathways, with some involving the tricarboxylic...
Tag: <span>major depression</span>
Post
Search for a major depression trigger reveals a familiar face: Discovery opens new possibilities for treatments
by University of Florida A model shows how glycine molecules (teal) interact with brain cell receptors called GPR158 to influence the nervous system. The dotted lines show hydrogen bonds and weak electrical field attractions that start the signal. Credit: Martemyanov lab at The Wertheim UF Scripps Institute. A common amino acid, glycine, can deliver a...
Post
Mitochondrial deterioration linked to major depression in older adults
by Kim Krieger, University of Connecticut Credit: Pixabay/CC0 Public Domain Depression can drain a person’s energy. In the elderly, there may be a very good reason for that: depression has been linked with the deterioration of the tiny power plants in our cells. These power plants are the mitochondria, tiny structures within our cells that handle several...
Post
Researchers reveal possible molecular blood signature for suicide in major depression
by University of California, Irvine Credit: CC0 Public Domain A University of California, Irvine-led team of researchers, along with members of the Pritzker Research Consortium, has developed an approach to identify blood biomarkers that could predict the suicide risk of major depressive disorder (MDD) patients. The study, titled “Identification of potential blood biomarkers associated with suicide in...
Post
Novel Medication Tied to Better Quality of Life in Major Depression
Nancy A. Melville April 05, 2022 DENVER ― An investigational once-daily oral neuroactive steroid is linked to significant improvement in quality of life (QoL) and well-being in patients with major depressive disorder (MDD), new research shows. In a phase 3 trial that included more than 500 adult patients with MDD, those who received zuranolone for...
Post
Study suggests postpartum depression differs from major depression
by University of Otago Credit: CC0 Public Domain Women with postpartum depression experience smell differently than other women, a University of Otago study has found. Lead author Dr. Mei Peng, of the Department of Food Science, says the findings add further evidence to the growing argument that postpartum depression is different from major depression, and requires...
Post
Brain scientists haven’t been able to find major differences between women’s and men’s brains, despite over a century of searching
People have searched for sex differences in human brains since at least the 19th century, when scientist Samuel George Morton poured seeds and lead shot into human skulls to measure their volumes. Gustave Le Bon found men’s brains are usually larger than women’s, which prompted Alexander Bains and George Romanes to argue this size difference...
Post
Autism: How a gene alteration modifies social behavior
Researchers report on a treatment approach that could normalize social behavior in autism UNIVERSITY OF BASEL A team of researchers at the Biozentrum, University of Basel, has discovered a new connection between a genetic alteration and social difficulties related to autism: A mutation in the neuroligin-3 gene reduces the effect of the hormone oxytocin. In...
Post
Major depressive episodes far more common than previously believed, new Yale study finds
Major Depressive Episodes Far More Common than Previously Believed, New Study Finds The number of adults in the United States who suffer from major depressive episodes at some point in their life is far higher than previously believed, a new study by the Yale School of Public Health finds. National survey data currently shows that...
Post
Salmonella biofilm protein causes autoimmune responses—possible link with Alzheimer’s, Parkinson’s
Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre (VIDO-InterVac) at the University of Saskatchewan (USask) and Temple University in Philadelphia, Penn., have demonstrated that a salmonella biofilm protein can cause autoimmune responses and arthritis in animals. Salmonella was previously thought to only form biofilms in the environment, such as on food processing surfaces....
- 1
- 2