Ashley Gallagher, Associate Editor Gepirone hydrochloride ER (Exxua; Fabre-Kramer Pharmaceuticals Inc) is in a new class of antidepressants, making it the first and only approved antidepressant that selectively targets serotonin 1A receptors. The FDA has announced the approval of gepirone hydrochloride extended-release (ER) tablets (Exxua; Fabre-Kramer Pharmaceuticals Inc) for the treatment of adults with major...
Tag: <span>major depressive disorder</span>
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Major depressive disorder blamed for major diseases
by Annabel Mansfield, University of South Australia Major depressive disorder—referred to colloquially as the ‘black dog’ – has been identified as a genetic cause for 20 distinct diseases, providing vital information to help detect and manage high rates of physical illnesses in people diagnosed with depression. Assessing risk factors between depression* and 925 diseases, a...
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Childhood trauma may affect brain structure, predisposing adults to recurring major depressive disorder
by Lancet Credit: CC0 Public Domain Early life trauma may affect the structure of the brain in a way that makes clinical depression more likely to be severe and recurrent, according to a two-year observational study of 110 patients published in The Lancet Psychiatry journal. Previous studies have suggested an association between maltreatment and altered brain structure, while...