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Researchers use CRISPR to build melanoma models from scratch using human cells
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Researchers use CRISPR to build melanoma models from scratch using human cells

by Allessandra Dicorato, Broad Institute of MIT and Harvard A histology image of a melanoma model. Credit: Science (2022). DOI: 10.1126/science.abi8175 By introducing cancer-causing mutations into healthy skin cells step-by-step, Broad scientists have created models of skin cancer that can reveal the effects of mutations. Over the last two decades, researchers have discovered thousands of genetic mutations in cancer, but...