Significantly more patients with stable bone mineral density after discontinuation of denosumab received zoledronate prior to initiation of denosumab EUROPEAN LEAGUE AGAINST RHEUMATISM Madrid, Spain, 13 June 2019: The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2019) finds the risk of bone mineral density (BMD) loss after denosumabdiscontinuation is associated with younger age, high bone turnover markers, and not receiving the bisphosphonate, zoledronate, prior to initiation of denosumab.1 The study followed 71 post-menopausal women who were classified...
Tag: <span>menopause</span>
Improving breast cancer treatment
Oestrogen receptive positive breast cancer can be treated by drugs, such as fulvestrant, that interfere with the action of oestrogen. Although these drugs are often effective for a while, the cancer can frequently become resistant and the drugs stop working. In the trial, researchers investigated whether they could reverse or delay resistance to hormone therapy in post -menopausal women whose cancer had...
Could the solution to osteoporosis be in the bile?
by Laura Alejandra Velazquez Villegas, The Conversation Osteoporosis is a degenerative disease where the bone density and quality are reduced. This disease is associated with substantial pain and disability leading to devastating long-term physical and psychological consequences. In Europe, the total osteoporosis economic burden was estimated at 30.7 billion euros in 2010, and is expected to reach 76.7 billion in...
Menopause ‘not the cause of midlife weight gain’ in women
by Australian National University Fat-mass continues to increase in middle-age women but menopause isn’t to blame, according to new research from The Australian National University (ANU). Mr Ananthan Ambikairajah, a Ph.D. Scholar from ANU, says post-menopausal women do have higher belly fat compared to premenopausal women, which could increase their risk of cardiovascular disease and dementia. “Older women can experience weight gain for many reasons....
FDA approves osteoporosis therapy for high-risk postmenopausal women
(HealthDay)—Evenity (romosozumab-aqqg) was approved for the treatment of osteoporosis in postmenopausalwomen with a high risk for fracture, the U.S. Food and Drug Administration announced. Evenity, a monoclonal antibody, blocks the effects of sclerostin and increases bone formation. It is indicated for use in postmenopausal women who have a history of osteoporotic fracture or risk factors for fracture and those who have failed or developed intolerance to other osteoporosistreatments. ...
A New Treatment for Menopause May Be on the Way
Researchers say a new type of drug that blocks a receptor in the brain could provide relief for women going through menopause. There’s good news for women going through menopause if you can wait three years or so. Credit: Getty Images Researchers say they’ve discovered that an experimental class of drugs that blocks a key...
How the New Blood Test for Menopause Can Help Women
Women who want to know if they have entered menopause — or when they will — may be able to find out with a new blood test. The U.S. Food and Drug Administration (FDA) recently granted approval to the PicoAMH Elisa test. It’s produced by Ansh Labs. The test works by measuring anti-Müllerian hormone (AMH),...
Stem cell therapy may help reverse effects of premature menopause, restore fertility
Young women with premature ovarian insufficiency (POI) may be able to use their own bone marrow stem cells to rejuvenate their ovaries and avoid the effects of premature menopause, new research suggests. The preliminary results from the ongoing ROSE clinical trial will be presented Tuesday at ENDO 2018, the 100th annual meeting of the Endocrine Society, in...
Do vitamins help with menopause?
As women start to produce less estrogen and enter perimenopause, they are likely to experience a mix of challenging symptoms. These include hot flashes, insomnia, night sweats, vaginal dryness, and mood swings. Menstrual periods may get lighter or heavier and less regular, but once a woman has not had a period for 12 months, they...