by Frontiers Journals Schematic illustration of the PAMRP theory of aging. Credit: Engineering (2024). DOI: 10.1016/j.eng.2024.09.010 Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called pro-aging metabolic reprogramming (PAMRP), which could change our understanding of aging. The traditional debate on aging has centered around whether it is a programmed...
Tag: <span>metabolic</span>
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Doctors could soon use facial temperature for early diagnosis of metabolic diseases
Peer-Reviewed Publication CELL PRESS IMAGE: AVERAGE FACIAL TEMPERATURES OF THREE AGING-STATUS GROUPS AMONG WOMEN 50-60 YEARS OLD CREDIT: ZHENGQING YU AND JING-DONG J HAN A colder nose and warmer cheeks may be a telltale sign of rising blood pressure. Researchers discovered that temperatures in different face regions are associated with various chronic illnesses, such as...
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Arterial stiffness may cause metabolic syndrome in adolescents via an increase in fasting insulin and LDL cholesterol
by University of Eastern Finland The presence of any three of high blood pressure, high trunk fat mass, high fasting glucose, high fasting triglyceride and low fasting high-density lipoprotein cholesterol describes metabolic syndrome. Arterial stiffness in adolescents measured with carotid-femoral pulse wave velocity may potentially cause metabolic syndrome in young adulthood via an increase in fasting...
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High aerobic fitness does not protect children from metabolic syndrome, study finds
by University of Jyväskylä Differences in V̇O2peak among children with different numbers of cardiometabolic risk factors. The metabolic syndrome was defined using the modified National Cholesterol Education Program definition and using the population specific highest 25th percentiles of waist circumference, HDL cholesterol (lowest 25th percentile), triglycerides, glucose, and blood pressure to define cut-offs for an increased...
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Researchers identify bacteria that promote metabolic and mental health
by University College Cork B. longum APC1472 increases Bifidobacterium abundance without impacting the overall composition of the gut microbiota in humans. The gut microbiota was assesed at the beginning (pre) and end of the study (12 weeks, past). Alpha (A-C) and beta diversity (D) were investigated, as wel as the bacterial genera present (E-F). Microbial taxa...
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Study examines the heart risks and benefits of today’s most popular fad diets
Researchers examine claims associated with keto and intermittent fasting ANDREW M. FREEMAN, MD, IS A CARDIOLOGIST AT NATIONAL JEWISH HEALTH. DR. FREEMAN IS IN THE DIVISION OF CARDIOLOGY AND DEPARTMENT OF MEDICINE. view more CREDIT: NATIONAL JEWISH HEALTH In a review of existing scientific studies on trendy ketogenic and intermittent fasting diets, researchers at National...
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New connections reveal how cancer evades the immune system
by University of Michigan If cancer is a series of puzzles, a new study pieces together how several of those puzzles connect to form a bigger picture. One major piece is the immune system and the question of why certain immune cells stop doing their job. Another piece involves how histones are altered within immune...
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Molecules in the blood of older people promote cancer spread
A molecule produced by the metabolism of proteins and fats has been found to accumulate in the blood of older people, and to endow cancer cells with the ability to spread from one site in the body to others. As we get older, the risk that we will develop cancer increases, because we accumulate genetic...
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How protein protects against fatty liver
DEUTSCHES ZENTRUM FUER DIABETESFORSCHUNG DZD MICROSCOPIC IMAGES OF LIVER BIOPSIES OF THREE INDIVIDUALS WITH DIFFERENT DEGREES OF LIVER FAT ACCUMULATION view more CREDIT: DIFE Non-alcoholic fatty liver disease is the most common chronic liver disease in the world, with sometimes life-threatening consequences. A high-protein, calorie-reduced diet can cause the harmful liver fat to melt away...
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A metabolic enzyme as a potential new target for cancer immune therapies
by German Cancer Research Center The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This was discovered by scientists at the German Cancer Research Center (DKFZ) and the Berlin Institute of Health (BIH). The enzyme that activates the dioxin receptor is produced in large quantities by tumor cells....