by Medical University of Vienna Research into use of diabetes medication for treatment of metastatic prostate cancer. Credit: 2015 Lightspring/Shutterstock Patients with localized prostate cancer have a good chance of survival, but mortality rates among those with advanced, metastatic forms of the condition remain high. Until now, the precise mechanism behind the spread of the tumor has...
by Dana-Farber Cancer Institute Credit: Pixabay/CC0 Public Domain Like the better-known prostate-specific antigen (PSA), prostate-specific membrane antigen (PSMA) is a biomarker that can tell physicians much about a patient’s metastatic prostate cancer. PSMA is a protein on the cell surface of most prostate cancers; scanning for it with positron emission tomography (PET) can indicate where...
UNIVERSITY OF TAMPERE An international research team has discovered a principle that explains the metastasizing of prostate cancer. When cancer evolves within the prostate, multiple spatially intermixed cancer cell clones are created that may invade the organs surrounding the prostate. However, only one dominant cell clone spreads systemically in the body and creates metastases. In...
In the past, all forms of metastatic prostate cancer have been considered incurable. In recent years, the FDA has approved six drugs for men with metastatic disease, all of which can increase survival. In a study published in Urology, researchers demonstrate for the first time that an aggressive combination of systemic therapy (drug treatment) with local...
