Tag: <span>Misfolding</span>

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Protein shapes matter in Alzheimer’s research
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Protein shapes matter in Alzheimer’s research

by Allison Mills, Michigan Technological University Sometimes proteins misfold. When that happens in the human brain, the pileup of misfolded proteins can lead to neurodegenerative diseases like Alzheimer’s, Parkinson’s and ALS. Proteins do not misbehave and misfold out of the blue. There is a delicate ecosystem of biochemical interactions and environments that usually let them...

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How Proinsulin Misfolding is a Prelude to Type 2 Diabetes

Posted Today An astounding 86 million people in the United States have prediabetes, a condition marked by elevated blood sugar that gives rise to type 2 diabetes. Of these individuals, 90% don’t know that they have the condition, which increases their risk of developing heart disease and stroke. When an individual has prediabetes, the increased...