News Release 19-Sep-2024 The study, published in Cell, reveals an essential function of sodium transport in cellular energy generation Peer-Reviewed PublicationCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) image: Jesús Vázquez Cobos, Iván López-Montero, Enrique Calvo Alcocer, Pablo Hernansanz Agustín, Carmen Morales Vidal, José Antonio Enríquez, Rebeca Acín Pérez, Sara Jaroszewicz and José Luis Cabrera...
August 31, 2024 by Rebecca Zhangqiuzi Fan and Kim Tieu, Florida International University Mitochondria produce the energy that fuels cells. Credit: OpenStax, CC BY-SAIn 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, Parkinson’s...
NEWS RELEASE 23-JUL-2024 Peer-Reviewed PublicationWALTER AND ELIZA HALL INSTITUTE IMAGE: MITOCHONDRIA (BLUE) BEING TARGETED BY MITOPHAGY (GREEN AND RED). CREDIT: WEHI Researchers at WEHI in collaboration with a team at the University of Vienna have discovered two proteins that act as regulators for mitophagy. Mitophagy is the process cells use to recycle damaged mitochondria, the...
by The Scripps Research Institute Alzheimer’s nerve cells manifest a decrease in the connections between nerve cells, called synapses, shown here within the blue circles. Half the synapse is marked with a red fluorescent stain and the other half with a yellow stain. Credit: Scripps ResearchNerve cells in the brain demand an enormous amount of energy...
by University of California – San Diego These colored streaks are mitochondrial networks within fat cells. Researchers from UC San Diego discovered that a high-fat diet dismantles mitochondria, resulting in weight gain. Credit: UC San Diego Health SciencesThe number of people with obesity has nearly tripled since 1975, resulting in a worldwide epidemic. While lifestyle factors...
What causes fatigue after exercise in people with long COVID? Image credit: M Stone/Stocksy.At least 65 million people globally have long COVID.The most common symptoms of long COVID include post-exertional malaise, cognitive impairment, brain fog, sleep problems, and fatigue, which can have a severe impact on a person’s life.Researchers are still unsure why some people...
Peer-Reviewed Publication UNIVERSITY OF COLOGNE PICTURES SHOW SMALL INTESTINAL VILLI FROM WILD TYPE (TOP) AND ENTEROCYTE-SPECIFIC DARS2 KNOCKOUT MICE (BOTTOM) STAINED FOR PLIN2 (YELLOW), TGN38 (RED), E-CADHERIN (GREEN) AND DNA (DAPI, BLUE). CREDIT: CHRYSANTHI MOSCHANDREA The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive amounts of fatty foods...
Nov 10 2023São Paulo Research Foundation (FAPESP) Researchers at the University of São Paulo (USP) in Brazil, partnering with colleagues in Australia, have identified a novel bacterial protein that can keep human cells healthy even when the cells have a heavy bacterial burden. The discovery could lead to new treatments for a wide array of...
by Julius-Maximilians-Universität Würzburg a Adoptive co-transfer of WT (tdTomato+GFP+) and HIF-1α-deficient (tdTomato+) P14 T cells into C57BL/6 mice before chronic infection with LCMV clone 13 (LCMVCL13). 21 days post infection (d.p.i.), donor P14 WT and HIF-1α-deficient T cells were FACS sorted, barcoded, and multiplexed in a 1:1 ratio and subjected to single-cell RNA sequencing. Uniform manifold...
by Laval University Endogenous mitochondrial mass in FECD cells influences mitochondrial internalization. (A) Mitochondrial mass markers (mitotracker) were used to label exogenous internalized (green) and endogenous mitochondria (red). (B) Both mitotracker signals were plotted, each dot representing a single cell. The mitochondrial mass appeared to be distributed according to two distinct clusters that could be arbitrarily...
