Tag: <span>Multiple sclerosis</span>

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High‑dose vitamin D significantly reduces disease activity in early multiple sclerosis onset, clinical trial finds

by Justin Jackson , Medical Xpress Credit: Unsplash/CC0 Public Domain Researchers from CHU Nîmes, Université Montpellier, and multiple MS centers in France have found that oral cholecalciferol in doses of 100,000 IU every two weeks significantly reduced disease activity in clinically isolated syndrome and early relapsing‑remitting multiple sclerosis. The study is published in the journal JAMA. Multiple sclerosis...

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NICE Expands Cladribine Access for Patients With Multiple Sclerosis

Dr Rob Hicks March 12, 2025 0 The National Institute for Health and Care Excellence (NICE) has recommended cladribine (Mavenclad, Merck Serono) for adults in England with relapsing-remitting multiple sclerosis (RRMS). This decision makes the NHS the first healthcare system in Europe to widely offer the at-home tablet for patients with active MS. The final draft guidance means cladribine...

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Out-of-balance gut bacteria are linked to multiple sclerosis—the ratio can predict severity of disease

by Ashutosh Mangalam, The Conversation Akkermansia is commonly found in the human gut microbiome. Credit: Zhang et al/Microbial Biotechnology, CC BY-SA Multiple sclerosis is a disease that results when the immune system mistakenly attacks the brain and spinal cord. It affects nearly 1 million people in the U.S. and over 2.8 million worldwide. While genetics play a role in the risk...

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Higher fish intake linked to reduced risk for multiple sclerosis disability worsening

by Elana Gotkine Higher fish consumption is associated with slower disability progression in multiple sclerosis (MS), according to a study published online Feb. 25 in the Journal of Neurology, Neurosurgery & Psychiatry. ADVERTISING Eva Johansson, Ph.D., from the Karolinska Institute in Stockholm, and colleagues examined the influence of fish consumption on disability progression in MS using data for 2,719 participants...

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New 4D brain map reveals potential early warning signs of multiple sclerosis

by National Institutes of Health Dynamics of cells and microenvironments in perivascular and periventricular zones.MS-like lesions form and expand near central veins and ventricles, enriched with SASP markers. Molecular and MRI biomarkers spatiotemporally define lesion stages. As lesions evolve, EAE-related (astrocyteEAE, oligodendrocyteEAE, OPCEAE, microgliaEAE, ependymaEAE, and VEEAE), proliferative (leukocyteCyc, microgliaCyc, and OPCCyc), and myelin-repairing (OPCdifferentiation) cells...

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Early Warning Signs of Multiple Sclerosis (MS) — And Why You Shouldn’t Ignore Them

Written by Mandy Armitage, MD | Reviewed by Frank Schwalbe, MD Updated on February 26, 2024print_outlinedemail_outlined Key takeaways: Table of contents Early MS signs CIS Risk of MS Symptoms Causes Diagnosis Early detection Treatments More information Bottom line References Subtle Symptoms of MS You Should Never Ignore 0 seconds of 3 minutes, 3 secondsVolume 90% 03:04 Featuring Michelle...

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High dietary fish intake may slow disability progression in multiple sclerosis, study suggests

by British Medical Journal Credit: CC0 Public Domain A high dietary intake of lean and oily fish may slow the progression of disability in people with multiple sclerosis (MS), suggests a comparative population-based study, published online in the Journal of Neurology Neurosurgery & Psychiatry. The anti-inflammatory and neuroprotective properties of the nutrients found in fish may be...

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Gut microbiome changes linked to multiple sclerosis, study finds

by Isabella Backman, Yale University Overview of study design. Credit: Neurology Neuroimmunology & Neuroinflammation (2025). DOI: 10.1212/NXI.0000000000200355 The gut microbiome comprises the trillions of bacteria and other microorganisms that live in our digestive tracts, and it has been increasingly connected to human health and disease. A new Yale study reveals significant differences between the gut microbiomes of individuals...

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Multiple sclerosis: Cell-catching implant helps identify successful treatment in mice

by University of Michigan Scanning electron microscopy image: The short, cylindrical implant resembles a sea sponge with many irregular oval pores. A 1 millimeter scale bar in the right hand corner denotes a 5 millimeter diameter and 2 millimeter height. Credit: University of Michigan A sponge-like implant in mice has helped guide a treatment that slowed...

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Severe COVID-19 may be a risk factor for multiple sclerosis

by Örebro Universitet Credit: CC0 Public Domain COVID-19 may be a risk factor for multiple sclerosis (MS). This has been shown by new research at Örebro University and Örebro University Hospital, Sweden. The study is published in the journal Brain Communications. “We saw a raised risk of MS among people who had severe COVID-19. However, only an extremely...