by Ludwig Maximilian University of Munich A nerve cell with its dendritic processes studded by synaptic spines (red) being contacted by brain-resident microglia cell (blue) in a mouse brain. Credit: Misgeld & Kerschensteiner Multiple sclerosis (MS) is a chronic inflammatory disease that affects the central nervous system, in which nerve cells are attacked by the patient’s...
The abnormal immune system response that causes multiple sclerosis (MS) by attacking and damaging the central nervous system can be triggered by the lack of a specific fatty acid in fat tissue, according to a new Yale study. The finding suggests that dietary change might help treat some people with autoimmune disease. Image credit: Stephanie...
by University of California, San Francisco Credit: CC0 Public Domain An international research team led by UCSF scientists has shown, for the first time, that gut immune cells travel to the brain during multiple sclerosis (MS) flare-ups in patients. These gut cells seem to be playing a protective role, helping drive MS symptoms back into remission. Scientists know...
by University of Virginia A drug that has shown promise for treating multiple sclerosis may actually make the debilitating disease worse, new research from the University of Virginia School of Medicine suggests. The drug has not yet made it to human trials for MS, but the UVA scientists are warning their fellow researchers to proceed extremely cautiously. In addition to worsening the disease in...
by Thomas Jefferson University The purified oligodendrocyte extracellular vesicles under an electron microscope. Multiple sclerosis (MS) is an autoimmune disorder that develops as the body’s immune system attacks the central nervous system. Specifically, it attacks the protective layer surrounding nerve cells, called the myelin sheath. Current MS therapies aim to counter this inflammatory response by suppressing...
by Adrianna MacPherson, University of Alberta Faculty of Medicine & Dentistry U of A researcher Christopher Power and his team found that administering an anti-inflammatory drug called VX-765 through the nose slowed the progression of multiple sclerosis in a preclinical model. Intranasal administration of an anti-inflammatory drug helped reduce disease progression in a preclinical model of...
by Emily Ayshford, University of Chicago Multiple sclerosis, an autoimmune disease of the central nervous system that affects millions worldwide, can cause debilitating symptoms for those who suffer from it. Though treatments exist, researchers are still searching for therapies that could more effectively treat the disease, or even prevent it altogether. Researchers at the Pritzker School of Molecular...
U of A researchers, precision health company team up to develop sensor small enough to wear behind the ear but powerful enough to reduce costly hospital visits. University of Alberta researchers are teaming up with a precision-health innovator to develop a low-cost wearable sensor to help people suffering from chronic neurologic conditions treat their illness remotely while reducing...
by Karolinska Institutet Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. People with multiple sclerosis (MS) gradually develop increasing functional impairment. Researchers at Karolinska Institutet have now found a possible explanation for the progressive course of the disease in mice and how it can be reversed. The...
UNIVERSITY OF CALIFORNIA – IRVINE IMAGE: REGULATORY T CELLS (GREEN) SHOWN INTERACTING WITH PATHOGENIC TH17 CELLS (RED) NEAR COLLAGEN FIBERS (BLUE) IN THE SPINAL CORD IN A MODEL OF MULTIPLE SCLEROSIS. Irvine, CA – September 21, 2020 – In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in...
