JOHNS HOPKINS MEDICINE In a bid to determine factors linked to the most debilitating forms of multiple sclerosis (MS), Johns Hopkins Medicine researchers say they have identified three so-called “complement system” genes that appear to play a role in MS-caused vision loss. The researchers were able to single out these genes — known to be...
Tag: <span>Multiple sclerosis</span>
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Scientists find molecular key to body making healthy T cells
Researchers seek new therapies to stop immune diseases CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER CINCINNATI – In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation of mature and...
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FDA approves Ofev® as the first and only therapy to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated ILD
Interstitial lung disease (ILD) is the leading cause of death among people with systemic sclerosis (SSc) or scleroderma Approval is based on results from the Phase III SENSCIS® study, the largest randomized controlled trial in SSc-ILD patients Ofev is already approved in the U.S. and more than 70 countries for the treatment of idiopathic pulmonary fibrosis (IPF) Ridgefield, Conn., September 06, 2019 – Boehringer...
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Team discovers surprise contributor to multiple sclerosis
Cells that scientists have largely ignored when studying multiple sclerosis are actually key contributors to MS development, new research from the University of Virginia School of Medicine shows. The discovery suggests new avenues for devising treatments and is a vital step toward finding a cure. Understanding Multiple Sclerosis Scientists had assumed that these cells, known...
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A better MRI marker for disability progression in multiple sclerosis
by Ellen Goldbaum, University at Buffalo A retrospective, five-year study of 1,314 patients with multiple sclerosis (MS) has found that atrophied brain lesion volume is the only marker from MRI scans that can accurately predict which patients will progress to the most severe form of the disease. Secondary progressive MS, known as SPMS, typically appears...
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Genomic map implicates broad immune cell involvement in multiple sclerosis
COLUMBIA UNIVERSITY IRVING MEDICAL CENTER The International Multiple Sclerosis Genetic Consortium (IMSGC) reports the results of its latest study, “Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility”, in the journal Science today: the highly productive collaborative group presents a new milestone in its efforts to understand the genetic basis of multiple...
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AAN issues guideline on vaccines and multiple sclerosis
by American Academy of Neurology Can a person with multiple sclerosis (MS) get regular vaccines? According to a new guideline, the answer is yes. The guideline, developed by the American Academy of Neurology (AAN), recommends that people with MS receive recommended vaccinations, including yearly flu shots. The guideline is published in the August 28, 2019, online issue of Neurology, the medical journal of the AAN,...
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Rejuvenating brain stem cells may hold key to future MS treatments
By Catharine Paddock PhD Fact checked by Paula Field Scientists have found a way to make older brain stem cells in rats more youthful. The discovery could lead to improved treatments for aging-related diseases that degrade the brain and nervous system. The research concerns oligodendrocyte progenitor cells (OPCs), which are a type of stem cell,...
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How childhood viral infections may later drive multiple sclerosis
By Maria Cohut Fact checked by Paula Field Childhood viral infections that reach the brain may prime it for the development of autoimmune conditions, such as multiple sclerosis, later in life — this is what a recent study that scientists conducted in mice seems to suggest. Recent research has shown that multiple sclerosis (MS) is the most...
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MS patients at a greater risk of cancer, new study suggests
New results of a 65-year follow-up study of nearly 7,000 Norwegian patients with multiple sclerosis (MS) suggest that patients may have a greater overall risk of developing cancer than the general population SPINK HEALTH (Oslo, Saturday, 29 June, 2019) New results of a 65-year follow-up study of nearly 7,000 Norwegian patients with Multiple Sclerosis (MS) suggest that patients may have a greater overall risk of developing cancer than the general population, with an especially high risk of cancer in respiratory organs, urinary organs and the central...