Researchers at the University of Toronto and UC San Francisco have discovered that the intestine is the source of immune cells that reduce brain inflammation in people with multiple sclerosis (MS), and that increasing the number of these cells blocks inflammation entirely in a preclinical model of the disease. The cells in question are plasma...
Tag: <span>Multiple sclerosis</span>
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FDA Accepts BrainStorm’s NurOwn® IND Application for Progressive Multiple Sclerosis
U.S. Phase 2 Study to Begin in First Quarter of 2019 NEW YORK, Dec. 17, 2018 — BrainStorm Cell Therapeutics Inc. (NASDAQ: BCLI), a leading developer of innovative autologous adult stem cell therapeutics for debilitating neurodegenerative diseases, today announced that the U.S. Food and Drug Administration (FDA) has accepted the Investigational New Drug (IND) application...
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Multiple sclerosis: Accumulation of B cells triggers nervous system damage
TECHNICAL UNIVERSITY OF MUNICH (TUM) B cells are important in helping the immune system fight pathogens. However, in the case of the neurological autoimmune disease Multiple Sclerosis (MS) they can damage nerve tissue. When particular control cells are missing, too many B cells accumulate in the meninges, resulting in inflammation of the central nervous system....
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New insights into the neural risks and benefits of marijuana use
Research released today underscores both the dangers and the therapeutic promise of marijuana, revealing different effects across the lifespan. Marijuana exposure in the womb or during adolescence may disrupt learning and memory, damage communication between brain regions, and disturbing levels of key neurotransmitters and metabolites in the brain. In Alzheimer’s disease, however, compounds found in...
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How salt can trigger inflammation in multiple sclerosis
Researchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (MS). In a new study published Oct. 29 in the journal Nature Immunology, they report just how salt can trigger the potentially disabling autoimmune disorder. Credit: CC0 Public Domain First author Tomokazu Sumida, a researcher...
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A man who received a stem-cell transplant for multiple sclerosis can walk and dance again after suffering from the disease for a decade
A man in England with multiple sclerosis can walk and dance for the first time in 10 years after receiving a stem cell transplant for the disease. Roy Palmer spent the last decade in a wheelchair without any feeling in his legs. He decided to undergo a procedure known as hematopoietic stem cell transplantation (HSCT) after seeing the results from a television program. Two days after receiving treatment, Palmer regained feelings in his legs. HSCT is still considered to be...
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What causes multiple sclerosis? What we know, don’t know and suspect
U.S. actress Selma Blair announced on the weekend she has been diagnosed with multiple sclerosis. “I have probably had this incurable disease for 15 years at least,” she wrote. “And I am relieved to at least know.” People exposed to low levels of sunlight are more likely to have MS than those who live in warm climates. Credit:...
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Kessler researchers show Speed of Processing Training effective in multiple sclerosis
The pilot study by MS research team finds improvements in neuropsychological tests and the performance of everyday life activities KESSLER FOUNDATION East Hanover, NJ. September 18, 2018. A recent article by Kessler Foundation researchers underscores the importance of processing speed in overall cognitive function in individuals with multiple sclerosis (MS) and their performance of everyday...
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B cells among factors leading to brain lesions in multiple sclerosis
A team of researchers from the University of Zurich and the University Hospital Zurich has shown that in multiple sclerosis it is not only specific T cells that cause inflammation and lesions in the brain. B cells, a different type of immune cell, also play a role. These cells activate T cells in the blood. This discovery...
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Study finds multiple sclerosis drug slows brain shrinkage
NIH-funded trial offers hope for disease with limited treatment options NIH/NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE Results from a clinical trial of more than 250 participants with progressive multiple sclerosis (MS) revealed that ibudilast was better than a placebo in slowing down brain shrinkage. The study also showed that the main side effects of...