by Georgia State University Credit: Unsplash/CC0 Public Domain Multiple sclerosis (MS) is a chronic neurological disease that affects the body’s central nervous system. It can limit a person’s mobility, impair physical and cognitive functions, and increase the risk of falling, collectively compromising quality of life. Cognitive impairment has been particularly difficult for researchers to address,...
by University of Geneva Demyelinated spinal cord of mice suffering from autoimmune disease. Top, at room temperature, and bottom, exposed to cold. Myelin is coloured in blue. The purple staining within the white matter (parts towards the edge of the histological section) shows demyelinated lesions that are reduced in the bottom image. Credit: © UNIGE –...
by Scott Montgomery, The Conversation Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit: Marvin 101/Wikipedia For most of the time since the first description of multiple sclerosis (MS) in 1868, the causes of this disabling disease have remained uncertain. Genes have been identified as important, which...
ANN & ROBERT H. LURIE CHILDREN’S HOSPITAL OF CHICAGO A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells. While investigating potential mechanisms of brain tumor...
by University of Alberta Faculty of Medicine & Dentistry Credit: Pixabay/CC0 Public Domain An immunological molecule called fractalkine can boost the production of brain cells that produce myelin, a key factor in diseases such as multiple sclerosis, according to recent research from the University of Alberta. Myelin is an insulating layer around nerves that is gradually worn away...
by National Multiple Sclerosis Society Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit: Marvin 101/Wikipedia Researchers at the National Institutes of Health, Johns Hopkins University, and others have published results of studies that map out the activity of genes, molecules, cells, and their interactions...
by Scott Montgomery, The Conversation Credit: New Africa/Shutterstock Multiple sclerosis (MS) is most often diagnosed between the ages of 20 and 50. Certain genes put a person at greater risk of getting this disease of the central nervous system, but scientists are still trying to understand the triggers. My colleagues and I have been studying these...
by Julie Langelier, Gladstone Institutes A new study led by scientists at Gladstone Institutes—Mark Petersen (left), Katerina Akassoglou (center), and Reshmi Tognatta (right)—identifies a promising therapy that could improve the repair of damaged myelin. Credit: Michael Short/Gladstone Institutes In the nearly 1 million Americans living with multiple sclerosis, the fatty substance that insulates the nerves of...
by University of Michigan Demyelination by MS. The CD68 colored tissue shows several macrophages in the area of the lesion. Original scale 1:100. Credit: Marvin 101/Wikipedia A recent Michigan Medicine study found that people newly diagnosed with multiple sclerosis experience a myriad of significant symptoms that often cluster together. The study, published in Multiple Sclerosis Journal, analyzed...
by Kessler Foundation A research scientist (left) supervises a participant with MS during a computer-based cognitive rehabilitation training session at Kessler Foundation. Credit: Kessler Foundation/Jody Banks In a review of recent literature, a team of researchers from Kessler Foundation conclude that cognitive rehabilitation programs are efficacious in treating multiple sclerosis-related cognitive dysfunction, and urge clinicians to consider...
