In a special report published today in the journal Blood, an international working group of experts in myelodysplastic syndromes (MDS) proposes – for the first time – the recognition of a distinct subtype of MDS based on the presence of a nonheritable genetic mutation that causes the disease. The mutation is found in approximately one...
Tag: <span>myelodysplastic syndrome (MDS)</span>
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Genetic testing helps predict disease recurrence in myelodysplastic syndrome
A DNA-based analysis of blood cells soon after a stem cell transplant can predict likelihood of disease recurrence in patients with myelodysplastic syndrome (MDS), a group of cancerous disorders characterized by dysfunctional blood cells, according to new research at Washington University School of Medicine in St. Louis. Such a practice could help doctors identify patients...
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Scientists close in on mystery surrounding dangerous blood syndromes
Genetically driven MDS enabled by gene linked to metabolism and oxygen in cells CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER CINCINNATI – Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes (MDS), which cause people to have immature, malfunctioning bone marrow cells that fuel a...
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Researchers show p300 protein may suppress leukemia in MDS patients
MIAMI, March 27, 2017 – Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have shown that p300, a protein that increases gene expression by attaching acetyl molecules to DNA, may stop myelodysplastic syndrome (MDS) from developing into acute myeloid leukemia (AML). The study was published in the journal Leukemia....