Engineers at the University of California San Diego have developed an experimental vaccine that could prevent the spread of metastatic cancers to the lungs. A model of human lungs – illustrative photo. New nanoparticle vaccine could curb cancer metastasis to lungs. Image credit: Robina Weermeijer via Unsplash, free license The key ingredients of the vaccine...
What is the best delivery method for cancer vaccines? A study in mice suggests intravenous might be best. Image credit: Ani Dimi/Stocksy. Researchers found that cancer vaccines are more effective in mice when delivered intravenously instead of subcutaneously. They found that intravenous delivery activates a T-cell response and remodels the tumor microenvironment. If these findings can be...
Cancers in humans have all sorts of ways to survive and thrive: Cells and tumors use devious means to deflect, deceive, and evade detection by our bodies’ immune systems. Take how they fend off anti-cancer vaccines, for example. Cancer cells in the body, whether singularly or consolidated, essentially cloak themselves through chemical secretions to remain...
CALIFORNIA INSTITUTE OF TECHNOLOGY IMAGE: THIS INFOGRAPHIC ILLUSTRATES THE NEW VACCINE, COMPOSED OF RBDS FROM EIGHT DIFFERENT VIRUSES. THE TABLE SHOWS THE BROAD SPECTRUM OF SARS-COV-2 VARIANTS AND RELATED CORONAVIRUSES THAT THE VACCINE INDUCES PROTECTION AGAINST. CREDIT: COURTESY OF WELLCOME LEAP, CALTECH, MERKIN INSTITUTE A new type of vaccine provides protection against a variety of...
Researchers in the University of Toronto’s Faculty of Applied Science & Engineering have discovered a dose threshold that greatly increases the delivery of cancer-fighting drugs into a tumour. The findings, published recently in the journal Nature Materials, provide a potentially universal method for gauging nanoparticle dosage and could help advance a new generation of cancer...
Laser light can be seen scattered by nanoparticles in a solution of the UTSW-developed nanovaccine. Researchers from UT Southwestern Medical Center have developed a first-of-its-kind nanoparticle vaccine immunotherapy that targets several different cancer types. The nanovaccine consists of tumor antigens — tumor proteins that can be recognized by the immune system — inside a synthetic...
