SEPTEMBER 17TH, 2024POSTED BY U. CHICAGO(Credit: Getty Images) TAGS : CANCER, NANOTECHNOLOGYUNIVERSITY : UNIVERSITY OF CHICAGO Researchers have developed a nanomedicine that increases the penetration and accumulation of chemotherapy drugs in tumor tissues and effectively kills cancer cells in mice. The study in Science Advances addresses a limitation of chemotherapy. Although chemotherapy is the primary...
Tag: <span>nanoparticles</span>
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Russian doll’ packaging developed at Imperial could boost drug delivery
News Release 29-Jul-2024 Peer-Reviewed PublicationImperial College London The new technology, which is in the early stages of development, has the potential to significantly enhance the effectiveness and reduce the side effects of drugs and vaccines. Drugs and vaccines can be delivered to the body using tiny packages called nanoparticles. The structures of these delivery particles...
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60 years in the making: Nanoparticles revolutionize nucleotide delivery
By Tarun Sai LomteReviewed by Susha Cheriyedath, M.Sc.Jul 10 2024 A recent perspective article published in the journal Nature Reviews Drug Discoverydiscussed the evolution of lipid nanoparticles (LNPs) for nucleic acid delivery. The authors, Pieter Cullis, Professor of Biochemistry and Molecular Biology at the University of British Columbia, and Philip Felgner, Professor of Physiology and...
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Gold Nanoparticles Improve Accuracy of Infectious Disease Testing
Composite polymer particles adorned with gold nanoparticles could improve the accuracy of infectious disease testing. Original story from Tohoku University Purple circles with small protrusions on a black background.GNDP particles Credit: Hiroshi Yabu By harnessing the power of composite polymer particles adorned with gold nanoparticles, a group of researchers have delivered a more accurate means...
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Sugar-coated gold nanoparticles can quickly eliminate bacterial infections, no antibiotics required
by National Institutes of Health Researchers were able to visualize biofilms in teeth treated with dextran-coated gold nanoparticles using photoacoustic imaging. Credit: Journal of Clinical Investigation (2023). DOI: 10.1172/JCI168485If left to their own devices, bacteria on our teeth or wounded skin can encase themselves in a slimy scaffolding, turning into what is called biofilm. These...
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Decorated Nanoparticles Prevent Allergic Reactions
Northwestern University researchers have developed the first selective therapy to prevent allergic reactions, ranging in severity from itchy hives and watery eyes to trouble breathing and even death.A scanning electron microscope image of nanoparticles (colorized in purple) that have successfully entered a mast cell To develop the new therapy, researchers decorated nanoparticles with antibodies capable...
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‘Plug-and-Play’ Nanoparticles Could Make it Easier to Tackle Various Biological Targets
Researchers at UC San Diego have developed modular nanoparticles that can be customized to target biological entities such as tumors, viruses or toxins.The surfaces of the nanoparticles are engineered to host biological molecules, making it possible to tailor the nanoparticles for applications from targeted drug delivery to neutralizing biological agents. Live cell fluorescent visualization of...
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Allergy-specific nanoparticles target immune cells, prevent anaphylaxis
By Paul McClure Researchers have created a nanoparticle decorated with antibodies that targets the cells responsible for allergic reactionsEvan A. Scott/Northwestern University Researchers have created a nanotherapy that selectively targets and shuts down the immune cells responsible for causing an allergic response in mice, preventing anaphylaxis. Able to be tailored to specific allergens, the novel nanomedicine...
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Nanoparticles Get Lymphatic Vessels Pumping
By CONN HASTINGSMEDICINE, NANOMEDICINE, NEWS, ONCOLOGY, SURGERY Researchers at the Georgia Institute of Technology have developed a nanotechnological solution for lymphedema, a failure of the lymphatic system that results in uncomfortable and irreversible fluid retention. Previous research efforts have focused on trying to grow new lymphatic vessels, but these researchers have taken a different approach,...
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Lipid Nanoparticles That Deliver mRNA to T Cells Hold Promise for Autoimmune Diseases
Autoimmune disorders are among the most prevalent chronic diseases across the globe, affecting approximately 5-7% of the world’s population. Emerging treatments for autoimmune disorders focus on “adoptive cell therapies,” or those using cells from a patient’s own body to achieve immunosuppression. These therapeutic cells are recognized by the patient’s body as ‘self,’ therefore limiting side...