Integration of vascular risk factors with genetic susceptibility in neurological diseases. Credit: Cell (2024). DOI: 10.1016/j.cell.2024.09.018 The question of what causes complex neurological diseases such as Alzheimer’s or multiple sclerosis continues to confound scientists and doctors, with the unknowns standing in the way of early diagnoses and effective treatments. Even among identical twins who share the same genetic risk factors,...
Tag: <span>neurologic disease</span>
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Decoding the mysteries of medically unexplained neurologic diseases
by Greg Bruno, Rutgers University PCA analysis of 1789 proteins quantified in all 15 CFS-only and 15 CFS + FM CSF samples. ANOVA analysis revealed a total of 14 proteins with p value <.05; however, none of these proteins has an adjusted p value <.05. There is no clear separation of the two groups using their entire CSF proteome profiles....
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Potential therapy for rare neurologic disease
by University of Cincinnati A targeted therapy, currently being studied for treatment of certain cancers including glioblastoma, may also be beneficial in treating other neurologic diseases, a study at the University of Cincinnati shows. The study, being published online April 6 in the journal EBioMedicine, revealed that the effects of a therapy delivery system using...
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Stem cells help explain varied genetics behind rare neurologic disease
Researchers at Case Western Reserve University School of Medicine have successfully grown stem cells from children with a devastating neurological disease to help explain how different genetic backgrounds can cause common symptoms. The work sheds light on how certain brain disorders develop, and provides a framework for developing and testing new therapeutics. Medications that appear...