by Tokyo Metropolitan Institute of Medical Science Schematic model of sustained activation of TrkB signaling in the absence of BDNF. Credit: TMIMS Glaucoma is the leading cause of irreversible blindness due to optic nerve damage and the death of retinal ganglion cells (RGCs). Presently, reducing intraocular pressure is the sole evidence-based therapy for glaucoma patients,...
by National Eye Institute Credit: CC0 Public Domain A form of gene therapy protects optic nerve cells and preserves vision in mouse models of glaucoma, according to research supported by NIH’s National Eye Institute. The findings suggest a way forward for developing neuroprotective therapies for glaucoma, a leading cause of visual impairment and blindness. The report...
SHINSHU UNIVERSITY IMAGE: NEURITE ELONGATION PROMOTING ACTION view more CREDIT: COPYRIGHT 2021, HISANO ET AL., SHINSHU UNIVERSITY Lysophospholipids are phospholipids that have just one fatty acid chain, and in recent years, the role of lysophospholipids in physiology and pathophysiology has attracted attention. Lysophosphatidylethanolamine (LPE) is a type of lysophospholipid that are reportedly present in the brain that consist...
