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New findings could be life-changing for genetic syndrome sufferers
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New findings could be life-changing for genetic syndrome sufferers

by QIMR Berghofer Credit: Unsplash/CC0 Public DomainAn international research team led by QIMR Berghofer and Peter MacCallum Cancer Center has discovered that people with the hereditary cancer disorder Li Fraumeni syndrome are at greater risk of a much broader spectrum of cancers than previously thought. Li Fraumeni syndrome is a rare but devastating condition, which...

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New findings shed light on the role of platelets in patients with cirrhosis

Study results could point to new possibilities for personalised therapeutic approaches Peer-Reviewed Publication MEDICAL UNIVERSITY OF VIENNA Next to other complications, cirrhosis is also linked to abnormalities in haemostasis. However, the role of alterations in platelet function had previously been insufficiently investigated. Now, researchers at the Medical University of Vienna have shed light on the...

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New findings reveal important insights into age-related nonresolving inflammation

by Elsevier Resolvin-D2 (RvD2), when added ex vivo, acted directly on the bone marrow to induce a specific increase in monocyte/macrophage progenitors and reduce steatosis and collagen deposition. Credit: The American Journal of Pathology Aging is associated with chronic, nonresolving inflammation, or “inflammaging,” that can lead to tissue dysfunction. New findings reported in The American Journal...

New findings on therapy-related myeloid cancers
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New findings on therapy-related myeloid cancers

by Sylvester Comprehensive Cancer Center  Credit: Blood (2022). DOI: 10.1182/blood-2022-158992 Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs). These findings from Sylvester’s Myeloma Research Institute highlight the importance of fully...

New findings on therapy-related myeloid cancers
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New findings on therapy-related myeloid cancers

by Sylvester Comprehensive Cancer Center  Credit: Blood (2022). DOI: 10.1182/blood-2022-158992 Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs). These findings from Sylvester’s Myeloma Research Institute highlight the importance of fully...

New findings for the function of tau in neurodegenerative disease
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New findings for the function of tau in neurodegenerative disease

by Buck Institute for Research on Aging  Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration. Credit: The Buck Institute for Research on Aging Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the “tau interactome” uncovering new findings about the role of tau in neurodegenerative disease. Publishing in Cell, scientists found that...