NEWS RELEASE 3-JUL-2024 Adding newly ID’d compound makes naloxone more potent, longer lasting, mouse study shows Peer-Reviewed PublicationWASHINGTON UNIVERSITY SCHOOL OF MEDICINE The ongoing opioid epidemic in the U.S. kills tens of thousands of people every year. Naloxone, sold under the brand name Narcan, has saved countless lives by reversing opioid overdoses. But new and...
Tag: <span>Opioid</span>
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Buprenorphine Cost a Potential Barrier for Opioid-Addicted Youth, Adults
by Jennifer Henderson, Enterprise & Investigative Writer, MedPage Today August 7, 2023 article For young people with opioid use disorder (OUD), buprenorphine costs have declined overall but with drastic variation by payer type, researchers found. Examining buprenorphine prescriptions dispensed for U.S. youth ages 12 to 19, mean daily out-of-pocket costs declined 57.6% from 2015 through 2020 (from $4.03...
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Study examines the differences between opioid receptor subtypes
by Ingrid Fadelli , Medical Xpress Each opioid receptor subtype displays specific sequences or “barcodes” recognized by regulatory proteins. This unique network of interacting proteins will dictate its localization and signaling, thus impacting its physiological functions such as induced analgesic effects. Credit: Jade Degrandmaison. Opioid receptors are proteins in the central nervous system that are...
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Bridge, The Opioid Withdrawal Therapy Device, Released by Masimo
Masimo has announced that it’s making the Bridge device available, the first electronic therapeutic solution for tackling opioid withdrawals. Originally developed by Innovative Health Solutions, a Versailles, Indiana firm, the Bridge delivers neuromodulation to a set of occipital and cranial nerves (V, VII, IX, and X) via electrodes attached near the ear. The therapy helps...
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Rating pain is not just a numbers game
by Bob Marcotte, University of Rochester Medical Center “Is your pain tolerable?” A new study out today from the JAMA Network found that this simple question, used in conjunction with the traditional 0-10 rating scale posed to patients, could help doctors better understand whether treatments for pain, including opioid medications, are actually necessary. “Because of...
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Pharmacy Chains Sue Ohio Physicians Over Opioid Prescribing
Ken Terry Several large pharmacy chains have sued 500 unnamed doctors in northeast Ohio as part of the sprawling litigation that has arisen from the opioid epidemic, The Washington Post recently reported. The federal lawsuit alleges that opioid prescribers bear some of the responsibility for the overuse of these powerful drugs, which have killed more...
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Virtual reality illuminates the power of opioid-associated memories
AMERICAN COLLEGE OF NEUROPSYCHOPHARMACOLOGY The number of drug overdose deaths in the US has never been higher. Most of those deaths–68 percent in 2017–have involved opioids. An estimated 10 million Americans aged 12 and older misused opioids in 2018. Insights from virtual reality experiments could help break the cycle of addiction, suggests new research from...
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Tramadol is an odd, unpredictable opioid, scientists say
by The Associated Press In this Thursday, Oct. 31, 2019, photo, a recovering tramadol drug addict signs a register after taking her medication at a de-addiction center in Kapurthala, in the northern Indian state of Punjab. India has twice the global average of illicit opiate consumption. Researchers estimate 4 million Indians use heroin or other...
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Novel research aims to identify new medications for the treatment of opioid use disorder
UNIVERSITY OF PENNSYLVANIA SCHOOL OF NURSING PHILADELPHIA (OCTOBER 31, 2019) – Opioid use disorder and overdose deaths are a major public health crisis in the United States. While medication-assisted treatments for opioid use disorder exist, these treatments remain inadequate for many patients, resulting in a high rate of relapse following detoxification. A new study from...
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Long-term opioid use has known link to low testosterone but not many men screened, treated
by University of Texas Medical Branch at Galveston Long-term opioid use previously has been linked with low testosterone in men. What has been unclear is how many men taking opioids had been screened or treated for low testosterone. A new study by researchers from The University of Texas Medical Branch at Galveston has found a...