by University of Michigan Axial CT image with i.v. contrast. Macrocystic adenocarcinoma of the pancreatic head. Credit: public domain One of the reasons pancreatic cancer remains the most deadly of the major cancers is that it craftily rewires normal cell survival mechanisms to keep itself supplied with nutrients to fuel its expansion. A new study led...
Tag: <span>Pancreatic cancer cells</span>
Nerves keep pancreatic cancer cells from starving
by NYU Langone Health Electron microscopic image of a single human lymphocyte. Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online November 2 in Cell. The study addresses pancreatic ductal...
New treatment triggers self-destruction of pancreatic cancer cells
Research conducted on human pancreatic tumors transplanted in mice reveals promising results, Tel Aviv University researchers say AMERICAN FRIENDS OF TEL AVIV UNIVERSITY Pancreatic cancer is resistant to all current treatments. Patients have extremely poor chances of surviving for five years after being diagnosed. A new Tel Aviv University study finds that a small molecule...
New path forward for pancreatic cancer treatment
Pancreatic cancer is one of the most aggressive cancers – by the time most cases are diagnosed, the cancer is advanced and spreading to other parts of the body. But what if these spreading cancer cells could, in fact, hold the key to guiding better treatment? Dr. Omid Faridani, recipient of the 2019 Pathfinders Award,...
Silencing RNA nanotherapy shows promise against pancreatic cancer
by University of South Florida Despite advances in cancer survival, more than 90 percent of people with pancreatic cancer die within five years. Most patients with pancreatic tumors (and half of those with colorectal cancers) carry a mutation in the KRAS gene, which normally controls cell growth and death. The KRAS oncogene was discovered more...
Genetic mutation may increase risk of pancreatic cancer in females
LONDON, ON – In a new study from Lawson Health Research Institute and Western University’s Schulich School of Medicine & Dentistry, researchers have found that mutation of a gene called ATRX may lead to increased risk of developing pancreatitis and pancreatic cancer in females. The study marks the first time a sex-specific genetic risk factor...
Role of rogue protein PAK4 confirmed in pancreatic cancer cells
A new study that confirms the role of a protein called PAK4 in the movement and growth of pancreatic cancer cells could help researchers find new ways to tackle the disease. The work, funded by national charity Pancreatic Cancer Research Fund, uncovers new evidence that PAK4 plays a key role in enabling cancer cells to...