Tag: <span>Paracetamol</span>

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Interruption of bile acid uptake by liver cells after paracetamol overdose mitigates liver damage
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Interruption of bile acid uptake by liver cells after paracetamol overdose mitigates liver damage

by Anne Rommel, Leibniz-Institut für Arbeitsforschung an der TU Dortmund  Graphical abstract. Credit: Journal of Hepatology (2022). DOI: 10.1016/j.jhep.2022.01.020 Poisoning with paracetamol (acetaminophen—APAP) is a common cause of liver failure. However, not all the correlations that lead to liver damage from APAP are yet known. Especially the role of bile acids is unclear. The Leibniz Research Center...

Using paracetamol for protecting kidneys in patients with severe malaria
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Using paracetamol for protecting kidneys in patients with severe malaria

by Menzies School of Health Research  Credit: Pixabay Paracetamol is used in many illnesses for the relief of pain and fever, but a study just published in Clinical Infectious Diseases has shown that it may also help protect against kidney damage in patients with malaria. The study led by former Menzies Ph.D. student Daniel Cooper with A/Professors...

FDA Approves Oliceridine, An Intravenous Opioid Severe Acute Pain Relievers for Clinical Use
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FDA Approves Oliceridine, An Intravenous Opioid Severe Acute Pain Relievers for Clinical Use

The United States Food and Drug Administration recently approved Oliceridine, also known as “Olinvyk,” an opioid primarily concerned in treating severe acute pain, by biopharmaceutical company, Trevena, last August 7, 2020. After years of getting the FDA to approve the drug, Trevena, Inc., finally received approval this year. Trevena initially submitted the drug for review...

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Easy to overdose on paracetamol if you’re selenium deficient, says research

People low on selenium are at risk of paracetamol overdose, even when they follow dosage recommendations, according to research involving the University of Bath in the UK. UNIVERSITY OF BATH A lack of the mineral selenium in the diet puts people at risk of paracetamol overdose, even when the painkiller is taken at levels claimed...