August 7, 2024 by American Academy of Neurology Immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson’s disease. Credit: WikipediaThere’s some good news for people with Parkinson’s disease: The risk of developing dementia may be lower than previously thought, or dementia may occur later in the course...
by Katherine Gaither, University of Alabama at Birmingham Credit: Unsplash/CC0 Public Domain Common treatments for Parkinson’s disease can address short-term symptoms, but can also cause extensive problems for patients in the long run. Namely, treatments can cause dyskinesia, a form of uncontrollable movements and postures. In a recent study published in The Journal of Neuroscience,...
Written by Katie E. Golden, MD | Reviewed by Patricia Pinto-Garcia, MD, MPH Updated on October 2, 2023 Key takeaways: The early signs of Parkinson’s disease can be subtle. They include loss of smell, constipation, trouble sleeping, and change in bladder habits.Many of the early symptoms of Parkinson’s start years before the more noticeable symptoms....
In the quest for better health, many people turn to supplements to fill nutritional gaps and boost their overall well-being. However, according to neuroscientist Robert Love, some commonly taken supplements can actually be harmful to your brain if consumed in high doses. In a TikTok video, Love warned about the potential dangers of three specific...
Three more pesticides commonly used in the United States have now been linked to heightened Parkinson’s risk. Image credit: Abstract Aerial Art/Getty Images.Parkinson’s disease prevalence is growing fast, and similar to some other neurological conditions, its causes are unclear.The potential impact of chemicals that are toxic to neurons in the part of the brain affected...
by Ruhr-Universitaet-Bochum NEMO is associated with pathological protein aggregates. Credit: Nature Communications (2023). DOI:10.1038/s41467-023-44033-0 Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson’s disease. NEMO, a protein that is primarily associated with signaling processes in the immune system, prevents the deposition of protein aggregates...
By Paul McClure A study has found that four gut disorders are associated with an increased risk of developing Parkinson’s disease Depositphotos A new study has found that particular gastrointestinal disorders are associated with an increased risk of developing Parkinson’s disease. The research provides further evidence to support the hypothesis that the neurodegenerative disorder begins in...
Peer-Reviewed Publication STANFORD UNIVERSITY Misfolded proteins are toxic to cells. They disrupt normal functions and cause some age-related human degenerative diseases, like Alzheimer’s, Parkinson’s, and Huntington’s diseases. Cells work constantly to eliminate misfolded proteins, but these clearance mechanisms are still poorly understood. In a new study published April 20 in Nature Cell Biology, researchers at Stanford University discovered...
by Rush University Medical Center Credit: Debashis Dutta et al, Cell Reports (2022). DOI: 10.1016/j.celrep.2022.111058 Regular treadmill exercise helped improve Parkinson’s disease symptoms in mice in a recent study by researchers at RUSH University Medical Center. The results of the study were recently published in the Cell Reports. “We’re very excited about the results,” said Kalipada Pahan, Ph.D., Floyd...
Constant V.M. Verschuur, M.D., from Amsterdam Neuroscience, and colleagues randomly assigned patients with early Parkinson disease to receive either levodopa (three times per day) in combination with carbidopa for 80 weeks (early-start group) or placebo for 40 weeks followed by levodopa in combination with carbidopa for 40 weeks (delayed-start group; 222 and 223 patients, respectively)....
