by Biophysical Society The top contributor to familial Parkinson’s disease is mutations in leucine-rich repeat kinase 2 (LRRK2), whose large and difficult structure has finally been solved, paving the way for targeted therapies. University of California, San Diego researchers Reika Watanabe, Robert Buschauer, Jan Böhning, Martina Audagnotto in the laboratory led by Elizabeth Villa used...