by Ciara O’shea, Trinity College Dublin What causes neurons to die in Parkinson’s disease? Parkinson’s disease is a long-term (chronic) neurological condition that affects around 12,000 people in Ireland and between 7 and 10 million people worldwide. The disease affects the way the brain co-ordinates body movements like walking and talking, but cognitive abilities are...
by Cedars-Sinai Medical Center People who develop Parkinson’s disease before age 50 may have been born with disordered brain cells that went undetected for decades, according to new Cedars-Sinai research. The research points to a drug that potentially might help correct these disease processes. Parkinson’s occurs when brain neurons that make dopamine, a substance that...
by KU Leuven Biomedical scientists at KU Leuven have discovered that a defect in the ATP13A2 gene causes cell death by disrupting the cellular transport of polyamines. When this happens in the part of the brain that controls body movement, it can lead to Parkinson’s disease. Parkinson’s disease is one of the most common neurodegenerative...
by IOS Press Overview of the currently included countries in the IPDGC and IPDGC-affiliated efforts. IPDGC = International Parkinson Disease Genomics Consortium, LARGE-PD = Latin American Research Consortium on the Genetics of Parkinson Disease, Lux GIANT = Luxembourg-German-Indian Alliance on Neurodegenerative diseases and Therapeutics. Credit: Laboratory of Neurogenetics, National Institute on Aging, National Institutes of...
CHINESE ASSOCIATION OF AUTOMATION arkinson’s disease is a neurodegenerative disorder that manifests through symptoms such as tremor, slow movements, limb rigidity and gait and balance problems. As such, nearly all diagnostic testing revolves around how a patient moves and requires the patient to walk for extensive distances and amounts of time. The discomfort caused to...
by IOS Press In order to optimally treat motor symptoms in patients with Parkinson’s disease (PD), it is necessary to have a good understanding of their severity and daily fluctuations. A report in the Journal of Parkinson’s Disease describes how a new app, SleepFit, could be a useful tool in routine clinical practice to monitor...
By Osman Shabir, M.Sc. | Reviewed by Dr. Jennifer Logan, MD, MPH Parkinson’s disease is a neurodegenerative disorder clinically characterized by dyskinesia (impairment of movement), resting tremor, bradykinesia (slow movements), dystonia (stiffness of muscles including facial muscles), a stooped posture, drooling, sexual and urinary dysfunction, and in some cases psychiatric symptoms including psychosis, dementia, and depression....
Reviewed by Kate Anderton, B.Sc. (Editor) Relatively new research findings indicating that the earliest stages of Parkinson’s disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson’s Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and...
Scientists review the evidence for using fecal transplantation and pre- and probiotics in patients with Parkinson’s disease in the Journal of Parkinson’s Disease IOS PRESS Amsterdam, NL, November 15, 2019 – Constipation is a common complaint in patients with Parkinson’s disease (PD). Fecal microbiome transplantation (FMT) and pre- and probiotics are potential options for treating...
Anne Pelletier-Cameron, M.D., often jokes to her patients that she’s a female plumber of the lower urinary tract. On a more professional note, however, she’s a urologist in the Michigan Medicine Department of Urology. In this role, Pelletier-Cameron treats patients with a variety of lower urinary tract symptoms. Some of her patients have been diagnosed...
