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Machine learning tool may diagnose Parkinson’s years before symptoms appear
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Machine learning tool may diagnose Parkinson’s years before symptoms appear

By Paul McClure May 10, 2023 New research has used a specially-designed machine learning algorithm to identify unique combinations of metabolites that may be able to detect Parkinson’s disease early Depositphotos Parkinson’s disease (PD) is growing more rapidly than any other neurological disease, which makes its early detection so important. Researchers have developed a new machine-learning tool that shows promise...

Early signals of Parkinson’s found in gut microbiota of REM sleep behavior disorder patients
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Early signals of Parkinson’s found in gut microbiota of REM sleep behavior disorder patients

by Justin Jackson , Medical Xpress Shifted microbial composition across the prodromal and early stages of α-synucleinopathy. a Principal coordinates analysis (PCoA) of microbial communities across control (n = 108), RBD-FDR (n = 127), RBD (n = 170), and early PD (n = 36) based on Bray–Curtis distance matrix at the genus level. The label of each group indicates group centroid. Boxplots along...

Zeroing in on Parkinson’s: Researchers take multifaceted approaches to brain disease
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Zeroing in on Parkinson’s: Researchers take multifaceted approaches to brain disease

by John H. Tibbetts, University of Georgia Anumantha Kanthasamy was recruited to UGA in 2021 as the inaugural John H. “Johnny” Isakson Chair and Georgia Research Alliance Eminent Scholar in Parkinson’s Research. After arriving in Athens, Kanthasamy immediately founded the Center for Neurological Disease Research and began building a network of faculty from around UGA to attack Parkinson’s and other neurodegenerative...

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Picking Up the Premotor Symptoms of Parkinson’s

Matthew F. Watto, MD; Paul N. Williams, MD April 05, 2023 This transcript has been edited for clarity. Matthew F. Watto, MD: Welcome back to The Curbsiders. We had a great discussion on Parkinson’s Disease for Primary Care with Dr Albert Hung. Paul, this was something that really made me nervous. I didn’t have a lot of comfort with...

World Parkinson’s Day: Doctors explain early warning signs people should not ignore
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World Parkinson’s Day: Doctors explain early warning signs people should not ignore

By – TIMESOFINDIA.COM Jigyasa Kakwani Created: Apr 11, 2023, 14:00 IST World Parkinson’s Day is observed on April 11th each year to raise awareness about Parkinson’s disease. It is a neurological disorder that affects millions of people worldwide, notes Dr. Jyoti Kapoor, Founder Director and Senior Psychiatric, Manasthali. Parkinson disease generally affects elderly people in...

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Removal of both ovaries in younger women associated with increased risk of Parkinson’s

MAYO CLINIC ROCHESTER, Minn. — Surgical removal of both ovaries is associated with an increased risk of Parkinson’s disease and parkinsonism in women younger than 43, Mayo Clinic researchers report in JAMA Network Open.  Using health record data from the Rochester Epidemiology Project, the study included 2,750 women who had undergone surgery to remove both ovaries, a procedure called bilateral oophorectomy, and...

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New focused ultrasound effective for treating Parkinson’s, movement disorders

UNIVERSITY OF NORTH CAROLINA HEALTH CARE VIDEO: UNC HOSPITALS AND UNC SCHOOL OF MEDICINE LEAD NATIONAL RESEARCH AND FDA-APPROVED USE OF FOCUSED ULTRASOUND TO HELP INDIVIDUALS WITH PARKINSON’S DISEASE. CREDIT: UNC DEPARTMENT OF NEUROSURGERY CHAPEL HILL, NC – In a study published in the New England Journal of Medicine co-authored by Vibhor Krishna, MD, associate professor of...

Common dry cleaning chemical linked to Parkinson’s
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Common dry cleaning chemical linked to Parkinson’s

by University of Rochester Medical Center Credit: Unsplash/CC0 Public Domain A common and widely used chemical may be fueling the rise of the world’s fastest growing brain condition—Parkinson’s disease. For the past 100 years, trichloroethylene (TCE) has been used to decaffeinate coffee, degrease metal, and dry clean clothes. It contaminates the Marine Corps base Camp...

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A Novel Treatment and Other Parkinson’s Updates From AAN 2022

Kathrin LaFaver, MD; Indu Subramanian, MD August 17, 2022 Kathrin LaFaver, MD: Welcome back, everyone. This is part two of our highlights from the American Academy of Neurology annual meeting abstracts in the movement disorders sphere, specifically in Parkinson’s disease, which were selected by Dr Indu Subramanian. Thanks again for joining us, Indu. Indu Subramanian, MD: Thank...

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IS PARKINSON’S REALLY MORE THAN ONE DISEASE?

In a postmortem analysis of brain neurons, researchers compared samples from 50 people who died with Parkinson’s and 50 who had no sign of the disease. They found more than 200 genes with different epigenetic marks in diseased and healthy brains—but the affected genes were almost entirely different in men and women. “WHAT WE CALL PARKINSON’S DISEASE,...