Tag: <span>PARP</span>

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Superfast DNA replication causes damage in cancer cells

Inhibitors of PARP proteins are used in cancer treatment. It emerges that PARP inhibitors exert their effect by accelerating DNA replication to a speed at which DNA damage occurs. The two strands of DNA’s double helix unwind to be copied, with a structure called a replication fork forming at the point of separation. The speed...