by University of Bristol Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington’s disease. The article, published in Brain Pathology, describes how SAFB1 expression occurs in both spinocerebellar ataxias and Huntington’s disease and may be a common marker of these conditions, which have a similar genetic background. SAFB1...
Tag: <span>Pathology</span>
It’s not just Alzheimer’s disease: Research highlights form of dementia
by University of Kentucky The long-running study on aging and brain health at the University of Kentucky’s Sanders-Brown Center on Aging Alzheimer’s Disease Center has once again resulted in important new findings—highlighting a complex and under-recognized form of dementia. The work was recently published in the Journal of the American Medical Association (JAMA): Neurology. “One...
Diagnosing brain tumors with a blood test
by University Health Network Dr. Daniel De Carvalho and Krembil Brain Institute Medical Director Dr. Gelareh Zadeh collaborated to combine advanced technology with machine learning to develop a highly sensitive and accurate blood test to detect and classify brain cancers. Credit: UHN A simple but highly sensitive blood test has been found to accurately diagnose...
Gold nanoparticles to save neurons from cell death
Published on ACS Nano, journal of the American Chemical Society, the study opens important perspectives for treatment of diseases such as Alzheimer’s and Huntington’s disease, but also epilepsy, brain trauma and stroke. ISTITUTO ITALIANO DI TECNOLOGIA – IIT CREDIT: IIT-ISTITUTO ITALIANO DI TECNOLOGIA Lecce, 25th June 2020 – Gold nanoparticles have been developed in the...
CANCER AND CHEMO TEAM UP TO MAKE NEUROPATHY WORSE
Contrary to common medical guidance, chemotherapy does not appear to be the only culprit in neuropathy, a neurological side effect of cancer treatment, according to a new study in rats. Cancer itself contributes heavily, too, and the stresses on neurons appear far worse than the sum of the two causes. “There was some distress caused...
Are Patients Dying ‘From’ COVID or ‘With’ COVID?
George D. Lundberg, MD DISCLOSURES June 05, 2020 Find the latest COVID-19 news and guidance in Medscape’s Coronavirus Resource Center. Death is usually fairly easy to diagnose; cause of death, not so much. In fact, death certificates in the United States and around the world are notoriously wrong. How does this happen? Death certificates are...
New method created for identifying genes behind brain tumors
by Uppsala University Researchers at Uppsala University have developed a method for identifying functional mutations and their effect on genes relevant to the development of glioblastoma—a malignant brain tumor with a very poor prognosis. The study is published in Genome Biology. The human genome consists of nearly 22,000 genes. Many studies have explored the nearly...
New cancer immunotherapy targeting myeloid cells slows tumor growth
Inhibiting a molecule hijacked by tumor cells to suppress the immune system shrank tumors PHILADELPHIA – Checkpoint inhibitors, a type of immunotherapy, that target myeloid immune cells and slow tumor growth were discovered by a team from the Perelman School of Medicine at the University of Pennsylvania and other institutions. Reporting in Nature Cancer, the...
Scientists identify a potential treatment candidate for early type 2 diabetic retinopathy
Diabetic retinopathy is one of the main vascular complications of type 2 diabetes, and the most common cause of visual deterioration in adults. A new study in The American Journal of Pathology reports on the efficacy of a possible treatment candidate that showed anti-inflammatory and neuroprotective effects on the retina and optic nerve head in...
Cracking the Lyme disease code
NEWS RELEASE 30-APR-2020 Cracking the Lyme disease code WASHINGTON STATE UNIVERSITY PRINT E-MAIL IMAGE: THIS IS ABDUL LONE. view more CREDIT: WSU The next time a tick feeds on you, Washington State University researchers hope to make sure persistent arthritis caused by Lyme disease doesn’t linger for a lifetime. Troy Bankhead, associate professor in WSU’s...