[LEFT] The higher-order structure of the kidney reconstructed from mouse ES cells (low magnification, green: collecting tube, red: nephron progenitor cells). [RIGHT] The nephron connected to the tip of the collecting tube (high …more In the embryonic kidney, three types of precursor cells interact to form three-dimensional structures of the kidney: nephron progenitor cells, ureteric...
Tag: <span>pluripotent stem cells (PSCs)</span>
Post
Reproducing higher-order embryonic kidney structures using pluripotent stem cells
[LEFT] The higher-order structure of the kidney reconstructed from mouse ES cells (low magnification, green: collecting tube, red: nephron progenitor cells). [RIGHT] The nephron connected to the tip of the collecting tube (high magnification, green: collecting tube, red: distal convoluted tubule, blue: proximal convoluted tubule, pink: glomus). In the embryonic kidney, three types of precursor...
Post
Recapitulation of Human Retinal Development from Human Pluripotent Stem Cells Generates Transplantable Populations of Cone Photoreceptors
Highlights hPSC-derived photoreceptors express markers in a pattern similar to human development 2D/3D differentiation protocol generates sufficient cones for transplantation hPSC-derived cones incorporate into the adult retina following transplantation Summary Transplantation of rod photoreceptors, derived either from neonatal retinae or pluripotent stem cells (PSCs), can restore rod-mediated visual function in murine models of inherited blindness....