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An Age-Related Increase in CD47 Expression Impairs Vascular Function
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An Age-Related Increase in CD47 Expression Impairs Vascular Function

This news or article is intended for readers with certain scientific or professional knowledge in the field. Researchers here provide evidence to indicate that increased expression of CD47 in aged blood vessels impairs a range of functions, from maintenance of these tissues to the generation of new blood vessels. The latter point is interesting given...

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Vitamin D twice a day may keep vertigo away

by American Academy of Neurology Taking vitamin D and calcium twice a day may reduce your chances of getting vertigo again, according to a study published in the August 5, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology. “Our study suggests that for people with benign paroxysmal positional vertigo,...

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Reducing corticosteroid use in rheumatoid arthritis

Large multinational study evaluates early discontinuation CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN Is the long-term use of glucocorticoids essential in people with chronic inflammatory diseases such as rheumatoid arthritis, or can early discontinuation prevent characteristic side effects? How can these drugs be discontinued without giving rise to glucocorticoid withdrawal syndrome? These were the questions addressed by the...

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Pimavanserin reduced symptoms of dementia-related psychosis in phase 3 trial

A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced risk of relapse of those symptoms compared to placebo in people with dementia, a condition for which no treatments are currently licensed UNIVERSITY OF EXETER A large-scale trial has found a treatment with pimavanserin substantially reduced psychotic symptoms and reduced...

Researchers detangle protein interaction implicated in Down syndrome and Alzheimer’s
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Researchers detangle protein interaction implicated in Down syndrome and Alzheimer’s

by Brittany Uhlorn, University of Arizona The powerful biomolecular NMR spectrometers at the University of Arizona have allowed scientists to gain molecular details of the interaction between RCAN1 and calcineurin, two proteins that have long been implicated in Down syndrome and Alzheimer’s disease. Credit: University of Arizona From the movement of a finger to the...

Different from a computer: Why the brain never processes the same input in the same way
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Different from a computer: Why the brain never processes the same input in the same way

MAX PLANCK INSTITUTE FOR HUMAN COGNITIVE AND BRAIN SCIENCES HOW STRONGLY THE CORTEX IS EXCITABLE BY A STIMULUS (LIGHTNING SYMBOL) IS NOT LEFT TO CHANCE. RATHER, THE CHANGE BETWEEN LOWER AND STRONGER EXCITABILITY FOLLOWS A CERTAIN TEMPORAL PATTERN (VIOLET… view more CREDIT: STEPHANI/ MPI CBS Rustling leaves, light rain at the window, a quietly ticking...

Brain tumors may originate in a brain region distinct from where it becomes a lethal disease
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Brain tumors may originate in a brain region distinct from where it becomes a lethal disease

by Children’s National Hospital A mouse model of glioblastoma, an aggressive type of cancer that can occur in the brain, suggests that this recalcitrant cancer originates from a pool of stem cells that can be a significant distance away from the resulting tumors. The findings of a new study, led by Children’s National Hospital researchers...

HIV pre-exposure drug regimen highly effective in preventing infection
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HIV pre-exposure drug regimen highly effective in preventing infection

A new drug regimen requiring injections every eight weeks have shown to be more effective in preventing HIV infection than one in which a pill must be taken daily, researchers from the HIV Prevention Trials Network (HPTN) announced at the 23rd International AIDS Conference. Emory University was a key participant in the study, enrolling seven...