Tag: <span>Proinsulin</span>

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First map of proinsulin’s ‘social network’ reveals new drug target for type 2 diabetes
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First map of proinsulin’s ‘social network’ reveals new drug target for type 2 diabetes

Study reveals previously unknown protein that helps proinsulin fold and opens new avenues for diabetes research SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Scientists at Sanford Burnham Prebys Medical Discovery Institute have mapped for the first time the vast network of proteins that interact with proinsulin, the protein the body normally processes into insulin. The study,...

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How Proinsulin Misfolding is a Prelude to Type 2 Diabetes

Posted Today An astounding 86 million people in the United States have prediabetes, a condition marked by elevated blood sugar that gives rise to type 2 diabetes. Of these individuals, 90% don’t know that they have the condition, which increases their risk of developing heart disease and stroke. When an individual has prediabetes, the increased...