Good News Network Mice on the right display graying and hair loss – Credit: MRC Laboratory of Medical Science / Duke-NUS Medical SchoolScientists have discovered that ‘switching off’ a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25%. The UK researchers at Medical Research Council Laboratory and Imperial College London,...
News Release 13-Aug-2024 Peer-Reviewed PublicationUniversity of Copenhagen – The Faculty of Health and Medical Sciences The study, published in the journal Cell, marks a step forward in the field of epigenetics and its impact on health and disease. Epigenetics, the study of how genes are turned on or off without changing the DNA itself, is...
NEWS RELEASE 25-JUL-2024 For the first time, researchers identify the mechanism that allows the varicella zoster virus to spread far from the infection site Peer-Reviewed PublicationUNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS VIDEO: THE VARICELLA ZOSTER VIRUS, WHICH RESIDES IN OVER 95% OF US, CAUSES CHICKEN POX AND THE MORE SERIOUS SHINGLES INFECTION. CUANSCHUTZ RESEARCHERS HAVE...
JULY 25, 2024 by University of Otago Model of the oxidation-induced amyloid formation and disassembly mechanism of p16. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-49581-7Researchers from the University of Otago, Christchurch, have spearheaded the discovery of a protein function which has the potential to guide the development of novel cancer treatment options and improve the diagnosis...
MARCH 1ST, 2024POSTED BY ERIC SLUSHER-U. MISSOURI“Not getting enough dietary protein is bad for health, but too much might also carry adverse health effects due to this macrophage signaling mechanism,” says Bettina Mittendorfer. “Our hope is to eventually find the Goldilocks approach for maximizing the health benefits of dietary protein, such as building lean muscle,...
by Anna Björklund, Identification of a conformational switch in c-MYC. a Overview of the MD strategy employed to identify regions that exhibit probe-induced conformational changes. b Normalized frequency distribution of Rg computed from the ensemble of structures generated from explicit solvent MD simulations in water (black) and water + benzene (red) for all nine c-MYC...
by University of Pittsburgh Credit: Unsplash/CC0 Public DomainUniversity of Pittsburgh School of Medicine researchers discovered a molecular mechanism by which excessive dietary protein could increase atherosclerosis risk. The findings were published in Nature Metabolism. The study, which combined small human trials with experiments in mice and cells in a Petri dish, showed that consuming over 22%...
New anti-cancer therapies could simultaneously deplete tumors of energy and boost the body’s immune response against them. (CREDIT: Creative Commons) Tumor cells are notorious for their adaptability and resilience in the face of treatment, often reshaping their energy metabolism to fuel their rapid growth and invasion. This metabolic shift not only sustains cancer cells but...
Scientists identify treatment target that disrupts proteins’ interaction, offering hope for new therapeutic approachPeer-Reviewed Publication CITY OF HOPE PROTEIN SURFACE (LEFT) AND RIBBON (RIGHT) MODELS OF INTEGRIN ΑV’S Β-PROPELLER DOMAIN ILLUSTRATE THE CAPACITY OF CPD_AV2 (YELLOW) IN DISRUPTING THE INTERACTION BETWEEN INTEGRIN Β5’S ΒA LOOP (CYAN; GREEN INDICATES THE KEY INTERACTING RESIDUE LYSINE 287) AND...
by Australian National University Credit: Pixabay/CC0 Public DomainA protein in the immune system can be manipulated to help overcome bowel cancer, according to new research from The Australian National University (ANU). The research is published in Science Advances. Bowel cancer claims more than 100 lives in Australia each week, yet around 90% of cases can be...
