By Pooja Toshniwal Paharia Jan 31 2023 Reviewed by Danielle Ellis, B.Sc. In a recent study published in Science Immunology, researchers investigated the CAMCI (combination of cell activation and metabolic checkpoint inhibition) strategy as an immunotherapeutic option for inflammatory bowel disease (IDB). Study: CD4+ T cell activation and concomitant mTOR metabolic inhibition can ablate microbiota-specific memory cells and prevent...
by University of Washington School of Medicine Laboratory research in immunology at the Ram Savan Lab at the University of Washington School of Medicine in Seattle. Credit: Ram Savan lab New research findings show in detail how self-reactive T cells—white blood cells that mistakenly attack healthy instead of infected cells, thereby causing an autoimmune or...
UNIVERSITY OF CALIFORNIA – IRVINE IMAGE: REGULATORY T CELLS (GREEN) SHOWN INTERACTING WITH PATHOGENIC TH17 CELLS (RED) NEAR COLLAGEN FIBERS (BLUE) IN THE SPINAL CORD IN A MODEL OF MULTIPLE SCLEROSIS. Irvine, CA – September 21, 2020 – In a new University of California, Irvine-led study, researchers have discovered how regulatory T cells (Treg) are instrumental in...
