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World-first use of base-edited CAR T cells to treat resistant leukemia
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World-first use of base-edited CAR T cells to treat resistant leukemia

by University College London Credit: Unsplash/CC0 Public Domain A patient with relapsed T cell leukaemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a ‘bench-to-bedside’ collaboration between UCL and Great Ormond Street Hospital for Children (GOSH). The patient, 13-year-old Alyssa from Leicester, was diagnosed with T-cell acute lymphoblastic leukaemia (T-ALL)...