August 30, 2024 by JooHyeon Heo, Ulsan National Institute of Science and Technology Schematic image, showing the blockade of the endocytic pathway by UNI418 in SARS-CoV-2-infected cells. Credit: Experimental & Molecular Medicine (2024). DOI: 10.1038/s12276-024-01283-2In light of the ongoing threat posed by new viruses following the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),...
by Jennifer L Reynolds, University of Georgia cup of teaCredit: Pixabay/CC0 Public DomainNew research from the University of Georgia suggests that something as simple as a cup of tea can help in the fight against COVID-19. Tea has been renowned globally for its many health benefits, and Malak Esseili, a virologist with the University of...
By Dr. Sanchari Sinha Dutta, Ph.D.Jan 23 2024Reviewed by Benedette Cuffari, M.Sc. In a recent study published on the medRxiv* preprint server, researchers conducted blood digital transcriptomics to determine the persistence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) in patients living with long-term consequences of coronavirus disease 2019 (COVID-19). Study: Blood...
by Mohit Nikalje, Indian Institute of Science RS2 sequence conservation and protective efficacy Top panel: Sequence conservation mapped onto a model of the RS2 molecule Bottom Panel: Lung tissue sections from mice demonstrate superior protection conferred by RS2 against viral challenge. Credit: Nidhi MittalSince the beginning of the COVID-19 pandemic, Raghavan Varadarajan, Professor at the Molecular...
An international research team, including Jonathan C. Schisler, PhD, in the UNC School of Medicine, has found how SARS-CoV-2 causes widespread “energy outages” throughout major organs, and how these effects contribute to debilitating long COVID sympto Peer-Reviewed Publication UNIVERSITY OF NORTH CAROLINA HEALTH CARE JONATHAN C. SCHISLER, PHD CREDIT: UNC DEPARTMENT OF PHARMACOLOGY CHAPEL HILL,...
by Pasteur Institute Clinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1. A, B Body weight variation over four days post-infection. C Lung weight measured at 4 dpi. D, E Clinical score over four days post-infection. The clinical score is based on...
by Lancet Credit: Pixabay/CC0 Public Domain Taking a two-week course of metformin, a safe and affordable diabetes medication after testing positive for SARS-CoV-2 leads to 40% fewer long COVID diagnoses over the following 10 months, compared to individuals taking a placebo, finds a new study published in The Lancet Infectious Diseases journal. The long-term symptoms some people experience...
by Anne Trafton, Massachusetts Institute of Technology Graphical abstract. Credit: ACS Central Science (2023). DOI: 10.1021/acscentsci.2c01471 Antibodies that can disarm a virus, known as neutralizing antibodies, are key to the body’s ability to fight off infection. MIT chemists have come up with a new way to identify these neutralizing antibodies in a blood sample, by analyzing how antibodies...
by The Scripps Research Institute Detailed structural imagery of public bnAbs and where they bind to SARS-CoV-2 (green helix) and MERS-CoV (orange helix). These bnAbs recognize the S2 region of the viral spike protein, which is relatively conserved and could lead to the development of a broad coronavirus vaccine and related antibody therapies. Credit: The...
FEBRUARY 14TH, 2023 CONN HASTINGS DIAGNOSTICS, MEDICINE, PUBLIC HEALTH Researchers at the Harvard Wyss Institute have developed an electrochemical device, called the eRapid sensor, that can assist clinicians in quickly characterizing someone’s COVID-19 infection, including identifying the infecting viral variant and the nature of someone’s immunity to the virus in terms of whether it is vaccine-mediated...
